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City of Hope

Research Associate II - Laboratory for Cellular Medicine (LCM) in the Center for Gene Therapy

Duarte, CA

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

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Position Summary:

A position of Research Associate II is open at the Laboratory for Cellular Medicine (LCM), Center for Gene Therapy. The candidate will join a well-established group performing cutting-edge research and clinical trials of gene and stem cell therapy, including first-in-human studies. This is a fast-paced laboratory performing work that includes pre-clinical research, development of GMP processes and GMP manufacturing for clinical trials, as well as QC and correlative studies associated with these trials. The candidate will be integrated in the LCM manufacturing team and will participate in the development and qualification of new processes and the manufacture of gene-modified cellular products or engineered grafts for clinical studies. The selected candidate will be trained in the necessary techniques and procedures and will have the opportunity to contribute to pioneering medical research.

The candidate will follow established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, including adherence to the workplace Code of Conduct and Compliance Plan. The candidate is expected to practice a high level of integrity and honesty in maintaining confidentiality. This position requires rigorous adherence to approved SOPs and worksheets, and accurate documentation of work performed and data. Work hours may vary, depending on the schedule of the manufacturing campaigns and clinical studies.

Key Responsibilities include:
  • Performs a variety of routine and non-routine laboratory research and manufacture experiments. Records and validates results for accuracy and completeness.
  • Troubleshoots procedures if experiment/procedure results are unexpected or unsatisfactory.
  • Responsible for accurately recording work performed including results and methodology.
  • Calculates, compiles, and analyzes data obtained from work performed. May contribute to the preparation of reports, manuscripts.
  • Trains laboratory staff in specialized procedures, methodologies and equipment use and maintenance. Keeps abreast of new and improved techniques.
  • Ensures that all laboratory activities are carried out in compliance with each procedure(s) by utilizing safety procedures and guidelines in handling, storage, and disposal of bio-hazardous, infectious and toxic material.
Basic education, experience and skills required for consideration:
  • A Bachelor's degree with 2 years of experience or Master's with 1 year of experience is required
  • Professional experience in research involving Cell Biology and Molecular Biology.
  • Preference will be given to candidates with some experience on cGMP and/or QC work and preparation of SOPs.
  • Preference will be given to candidates with experience on tissue culture techniques, processing and analyses of human cells, cell viability assays, staining and flow cytometry.
Additional Information:
  • For more information on Dr. Angelo Cardoso's research, visit here
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

  • Posting Date: Nov 5, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

Job ID: CityOfHope-10014088
Employment Type: Other