ZS is a place where passion changes lives. As a management consulting and technology firm focused on transforming global healthcare and beyond, our most valuable asset is our people. Here you'll work side-by-side with a powerful collective of thinkers and experts shaping solutions from start to finish. At ZS, we believe that making an impact demands a different approach; and that's why here your ideas elevate actions, and here you'll have the freedom to define your own path and pursue cutting-edge work. We partner collaboratively with our clients to develop products that create value and deliver company results across critical areas of their business including portfolio strategy, customer insights, research and development, operational and technology transformation, marketing strategy and many more. If you dare to think differently, join us, and find a path where your passion can change lives.
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Our most valuable asset is our people.
At ZS we honor the visible and invisible elements of our identities, personal experiences and belief systems-the ones that comprise us as individuals, shape who we are and
make us unique. We believe your personal interests, identities, and desire to learn are part of your success here. Learn more about our diversity, equity, and inclusion efforts and the networks ZS supports to assist our ZSers in cultivating community spaces, obtaining the resources they need to thrive, and sharing the messages they are passionate about.
Senior Bioinformatician - Nextflow Development
Discovery - Medical & Scientific Expertise Center
We help clients reinvent pharma discovery, elucidate disease biology, innovate novel therapeutics, and accelerate drug development to create breakthrough science and increase the probability of R&D success and patient outcomes. We're passionate about accelerating transformation in research and early development so clients can build capabilities in programmable biology across therapeutic modalities. Our integrated approach is multidisciplinary and led by science.
What You'll Do:
Creates and maintains 'omics' data processing / pipeline libraries and advises others on library governance by:
- Designing and coding analytical pipelines for various "omics" studies and experiments
- Providing support in the form of subject matter expertise to technical teams building bioinformatics platforms and research data lakes
- Evaluating, contrasting and recommending bioinformatics tools and platforms for client and commissioned projects, including capabilities from external partners and bioinformatics startups
- Performs other scripting/coding or bioinformatics tasks as required by the project
Plans for and executes data management, data cleaning and data integration activities by:
- Identifying and prioritizing the datasets and data sources relevant for a bioinformatics analysis or set of analysis
- Evaluating available extract-transform-load (ETL) solutions to extract the data or creating new ones
- Supporting customization, stewardship and governance of artifacts needed to keep the data clean and de-duplicated (eg. biomedical catalogs, dictionaries, vocabularies, taxonomies, ontologies and data quality rules and metrics)
- Publishing increments to the biomedical ontology as needed to capture all necessary data points
Creates or supports the creation of a strategy to deliver desired bioinformatics analysis outcomes by:
- Cataloguing and evaluating available biomedical & bioinformatics datasets and identifying their fit for purpose
- Identifying any gaps in the available biomedical data and research potential data partners to advance the project
- Proposing alternative datasets to use for a class of bioinformatics analytics problems, including strengths and weaknesses for each
Engages with biomedical science stakeholders to understand the expected bioinformatics analytics outcomes by:
- Learning about and understanding the hypothesis being tested, the entities involved (molecules, cells lines, samples, pathways, etc) and the laboratory techniques / assays used to test the hypothesis
- Collaborating with multi-disciplinary teams to frame scientific questions within a scientific problem space and any required background or insights
- Translating insights into design of bioinformatics studies and analysis
- Researching alternative bioinformatics methodologies and techniques to achieve the stated outcome or creating new ones as needed
Communicates the bioinformatics problem statement, state of the art, methodology, validation results in the form of:
- Peer-reviewed research papers in journals or scientific conferences
- Internal talks, client readouts and other non-public forums with clients and ZS teams
What You'll Bring:
- PhD in relevant field or 3-5 years relevant experience. Relevant degrees: Bioinformatics, Computational Biology, Genomics, Bioengineering, Biotechnology
- Must have solid experience with Nextflow DSL2
- Experience with Nextflow standards, nf-core and the Seqera Platform
- Experience with other data workflow managers (snakemake, CWL, etc.) is a strong advantage
- Must have experience with programming, statistical analysis (preferably Python or R), and working in a Linux/Unix environment
- Experience with NGS data analysis (RNAseq, WGS, etc.)
- Must be able to design and plan for bioinformatics / data processing pipelines as demonstrated by: 1) Having authored or co-authored a scientific communication that required the creation of a data processing pipeline or guidelines to create one, 2) Being able to walk the interviewer through the components necessary to resolve a complex data processing problem, and 3) Being able to understand a data processing pipeline and identify weaknesses / missing components
- Must have a strong background in bioinformatics, computational biology, or advanced data analysis as demonstrated by: 1) Co-author in at least one publication in relevant journals/conferences, or 2) Author or co-author of open-source packages (Groovy, Java, R, Python) used by the relevant communities
- Experience with cloud computing, HPC systems and job schedulers is a strong advantage
- Familiarity with Docker / Singularity
- Strong ability to interact professionally with co-workers and clients
- Excellent communication and presentation skills
- Strong visualization, reporting, and documentation skills
- Must be able to understand the logic flow of bioinformatics scripts and libraries and execute them
- Being able to talk about systems and coding problems that they have, address, and explain the intuition behind the solution
- Being able to diagrammatically draw the logic flow of a script that they have developed
Perks & Benefits:
ZS offers a comprehensive total rewards package including health and well-being, financial planning, annual leave, personal growth, and professional development. Our robust skills development programs, multiple career progression options and internal mobility paths and collaborative culture empowers you to thrive as an individual and global team member. We are committed to giving our employees a flexible and connected way of working. A flexible and connected ZS allows us to combine work from home and on-site presence at clients/ZS offices for the majority of our week. The magic of ZS culture and innovation thrives in both planned and spontaneous face-to-face connections.
Considering applying?
At ZS, we're building a diverse and inclusive company where people bring their passions to inspire life-changing impact in global healthcare and beyond. We are most interested in finding the best candidate for the job and recognize the value that candidates with all backgrounds, including non-traditional ones, bring. If you are interested in joining us, we encourage you to apply even if you don't meet 100% of the requirements listed above.
ZS is an equal opportunity employer and is committed to providing equal employment and advancement opportunities without regard to any class protected by applicable law.
To Complete Your Application:
Candidates must possess work authorization for their intended country of employment.
An on-line application, including a full set of transcripts (official or unofficial), is required
to be considered.
NO AGENCY CALLS, PLEASE.
Find Out More At:
www.zs.com