Life Science Research Professional 1 (1 Year Fixed Term)

The Department of Molecular and Cellular Physiology is seeking an experimental research associate (Life Science Research Professional 1) for a 1 year fixed term to join the Khan (YAK) Laboratory at Stanford University. The Khan Lab investigates RNA folding, RNA–protein interactions, and their cellular consequences using a highly interdisciplinary approach that integrates biochemistry, structural biology (cryo-EM/ET), and machine learning. The ideal candidate will join the team in September 2025 or shortly thereafter.

Lab overview

Cells rely on RNAs that adopt specific structures, engage proteins and other macromolecules, and regulate processes across viral and cellular contexts. The YAK Lab develops and applies biochemical and structural methods alongside computational/ML models to reveal the principles governing RNA structure, assembly, and function in cells and pathogens. Our research spans molecular mechanisms to cellular processes with applications to both basic science and human health.

Job description

We seek an enthusiastic, creative lab manager/research associate to help establish laboratory procedures, drive experimental projects on RNA structure and RNA–protein complexes, and support day-to-day operations of a growing group.

Representative projects may include:

• Reconstitution and biochemical/biophysical characterization of RNA–protein complexes.
• Sample preparation for cryo-EM/ET of RNA and RNP assemblies in vitro and (where appropriate) in cells.
• Cell-based assays to test how RNA structure and RBP interactions influence phenotypes in viral and cellular systems.
• Coordinating with computational collaborators to integrate ML predictions with experimental design and validation.

Qualifications

• Experience with molecular and cell biology techniques; strong preference for RNA biochemistry (e.g., in vitro transcription, RNA handling, nuclease assays) and/or protein purification.
• Experience with electron microscopy (cryo-EM/ET) workflows and/or structural biology is a plus.
• Familiarity with quantitative data analysis; comfort collaborating with ML/comp teams is welcome.
• High initiative, strong organization and time-management, excellent communication, and a collaborative mindset.
• Prior lab management experience (safety, inventory, ordering, equipment maintenance) is highly desirable.

Duties include

• Plan approaches to experiments in support of lab research based on knowledge of scientific theory.
• Independently conduct experiments; maintain detailed records of procedures, data, and outcomes.
• Apply life-science methods to analyze results; recommend protocol optimizations in collaboration with senior researchers.
• Stay current with the literature and apply relevant advances to ongoing projects.
• Contribute to publications and assist with figures, methods, presentations, and proposals.
• Help with general lab maintenance; maintain lab stock, manage chemical inventory and safety records, and provide general lab support.
• Assist with orientation and training of new staff or students on lab procedures and techniques.

– Other duties may also be assigned.

The expected pay range for this position is $31.40 to $38.89 per hour.
Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.

At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.
The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources at stanfordelr@stanford.edu. For all other inquiries, please submit a contact form.

Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

DESIRED QUALIFICATIONS:

EDUCATION & EXPERIENCE (REQUIRED):

Bachelor's degree in related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
• Ability to maintain detailed records of experiments and outcomes.
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Ability to work under deadlines with general guidance.
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

CERTIFICATIONS & LICENSES:

None

PHYSICAL REQUIREMENTS:
• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
• Must have correctible vision to perform duties of the job.
• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
• Ability to lift heavy objects weighing up to 50 pounds.
• Ability to work in a dusty, dirty, and odorous environment.
• Position may require repetitive motion.

- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

WORKING CONDITIONS:

• May require working in close proximity to blood borne pathogens.
• May require work in an environment where animals are used for teaching and research.
• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
• Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
• May require extended or unusual work hours based on research requirements and business needs.