Research Specialist - Quantitative Genomics

Summary:

We are currently searching for a Research Specialist to support the Quantitative Genomics shared resources lab. This opportunity is a full-time position onsite in Ashburn, VA. We are looking for a conscientious and self-motivated scientist who works well in a team environment and is eager to learn and improve their skills in a fast-paced work setting. This position offers the opportunity to develop new skills and learn best practices while gaining experience using the latest technologies.

About the role:

In this role, you will contribute to the Quantitative Genomics service mission by performing a wide range of advanced procedures and techniques to support upstream workflows, including tissue dissection from a variety of organisms, FACS and manual cell sorting, microdissection, nucleic acid isolation, and single-cell processing, as well as downstream library preparation, sequencing, and analysis. This would be an excellent role for a scientifically-minded professional with strong molecular biology technical skills who is interested in contributing to a team and supporting the research efforts underway on the Janelia Research Campus.

About Quantitative Genomics:

The Quantitative Genomics lab is a shared resource lab that provides a wide variety of expert services, including tissue dissection, microscopy, cell isolation, single-cell assays, transcriptome and epigenetic profiling, and genome assembly using next-generation sequencing platforms from Illumina & PacBio, and many more applications are in development. Our goal is to serve as a gateway to the rapidly evolving technologies for high-content genomic analysis for both experts and novices. From experimental design to data analysis, we are ready to help Janelians at any phase of a project. More information about our lab can be found here.

What we provide:

• A competitive compensation package, with comprehensive health and welfare benefits.
• One on one mentorship relationship with a senior researcher in the lab

What you'll do:

• Perform macro and microdissection, cell sorting and capture, microscopy, and single-cell assays.
• Support lab efforts by routinely employing molecular biology techniques including, but not limited to PCR, qPCR, RNA/DNA isolation, gel electrophoresis, and primer design.
• Operate a variety of complex instrumentation, including microscopes, vibratomes, FACS, liquid handling automation, and NGS sequencers.
• Perform high quality cDNA and library construction, including RNA/DNA purification and quality control using various instruments, including Qubit, Bioanalyzer, TapeStation, and Femto Pulse.
• Assist in the daily operation of the Quantitative Genomics lab by maintaining lab stocks, supplies and equipment, and other duties as assigned.
• Participate in team meetings and contribute to discussions on topics applicable to work performed in the shared resource.
• Support the team's commitment to maintain a workplace that embraces teamwork and inclusivity.

What you bring:

• MS in Biology or related discipline; plus 2 years of experience in next-generation sequencing and/or related field. An equivalent combination of education and relevant work experience will be considered.
• Experience performing tissue dissections, cell dissociation, nuclei prep, and proficiency in a wide variety of sample preparation methods.
• Capable of rapidly adapting to a variety of specimens and projects, often in parallel.
• Strong initiative, self-motivation, and capacity for creative problem solving.
• Strong verbal and written communication skills.
• Strong organizational skills, multi-tasking skills, and time management skills.
• Strong attention to detail and recordkeeping skills.
• Knowledge of Linux commands, Python, R or other bioinformatic tools are a plus.

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more.

Compensation Range
$67,540.00 (minimum) - $84,400.00 (midpoint) - $109,780.00 (maximum)

Pay Type:
Annual

HHMI's salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.

HHMI is an Equal Opportunity Employer