Director, Portfolio Decision Strategy

Position Description Summary

The Director, Portfolio Decision Strategy will play a pivotal role in partnering with senior leadership and project teams to embed decision quality process that guide strategic decisions and effective management of portfolio risks, directly influencing how resources and investments are allocated for maximum value creation. This influential position demands an experienced professional with a track record in leveraging decision analysis methodologies and advanced modelling techniques to spearhead strategic initiatives and enhance decision-making processes. The ideal candidate is an experienced decision-framework facilitator and decision-modeler, with a robust understanding of the biopharmaceutical industry, encompassing both commercial and R&D landscapes, and adept at stakeholder engagement to ensure balanced and widely supported decisions.

Main Responsibilities & Accountabilities

Strategic Decision Consultation and Facilitation:

• Serve as an internal consultant by collaborating with project teams to deliver specialized expertise in decision analysis and modelling.
• Implement structured decision-making methodologies and advanced modelling techniques to assess possible outcomes, navigate complex choices, and provide data-driven recommendations for team presentations to Governance.
• Lead project teams through scenario planning, risk assessment, and sensitivity analysis to support comprehensive assessments and informed strategic decisions.
• Lead and moderate high-impact workshops and collaborative sessions to distil decision objectives, surface creative solutions, and rigorously evaluate trade-offs, driving consensus and clarity in decision pathways.
• Lead and improve the PTRS (Probability of Technical and Regulatory Success) framework in partnership with Portfolio Development

Governance and Process Enhancement:

• Promote transparency, inclusiveness, and alignment with organizational objectives in portfolio decision-making processes.
• Develop and implement standardized processes and tools to ensure consistent application of portfolio decision analysis within the PD&C framework.
• Continuously evaluate, refine, and enhance the organization's decision-making frameworks by monitoring performance and responding agilely to business needs, offering strategic recommendations for advancement and innovation.

Capability Building and Mentorship:

• Design and deliver targeted training programs, tailored to build advanced decision analysis capabilities across project teams and stakeholders.
• Inspire a culture of continuous learning, excellence, and innovation in decision quality throughout the organization.
• Create case studies and disseminate success stories to highlight the impact and value of decision quality initiatives.

Key Stakeholders

Direct: TA Co-Leads, GPLs, Commercial Development, Portfolio Development, Business Development, Portfolio Insights Hub

Indirect: Portfolio Business Partners, Business Planning & Evaluations (BPE), Portfolio Finance, Global Insights & Analytics

Qualifications & Experience

• Bachelor's degree in business, economics, engineering, or life sciences. MBA or advanced scientific degree (MS, PhD) strongly preferred, with demonstrated understanding of pharmaceutical R&D processes and business fundamentals.
• Minimum 12+ years of biopharmaceutical industry experience with exposure to research, development, and/or commercialization processes. Deep understanding of drug development lifecycle, regulatory pathways, and commercial strategies.
• Direct experience with applied decision analysis methodologies, advanced R&D portfolio management techniques, Monte Carlo simulations, real options analysis, and/or data science applications in pharmaceutical settings.
• Experience in stakeholder engagement, ensuring balanced and widely supported decisions and perspectives.

Our Benefits

CSL employees that work at least 30 hours per week are eligible for benefits effective day 1. We are committed to the wellbeing of our employees and their loved ones. CSL offers resources and benefits, from health care to financial protection, so you can focus on doing work that matters. Our benefits are designed to support the needs of our employees at every stage of their life. Whether you are considering starting a family, need help paying for emergency back up care or summer camp, looking for mental health resources, planning for your financial future, or supporting your favorite charity with a matching contribution, CSL has many benefits to help achieve your goals.

Please take the time to review our benefits site to see what's available to you as a CSL employee.

About CSL Behring

CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.

CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.
We want CSL to reflect the world around us

At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. Learn more Inclusion and Belonging | CSL.

Do work that matters at CSL Behring!

Client-provided location(s): King of Prussia, PA

Job ID: CSL_FGB-R-260650

Employment Type: FULL_TIME

Posted: 2025-09-15T23:31:27