Research Technician I- G Protein- Lefkowitz Lab

Primary Work Address: MSRB 1, Suite 301, Research Drive, Durham, NC, 27710

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We are currently looking for a dynamic, driven, and curious Research Technician I within the lab of Dr. Robert Lefkowitz at Duke University in Durham, North Carolina. The lab seeks to understand the molecular mechanisms of a family of cell-surface proteins called G protein-coupled receptors (GPCRs) applying biochemical, medicinal-chemistry, structural, and cellular techniques. GPCRs are the targets of roughly one-third of all prescribed human therapeutics. More information on the work of the lab can be found on their website.

About the role:

We are looking for someone with a strong background in natural sciences who has a passion for continuing to push the boundaries of our understanding. This position will be working with two researchers within the lab who are working on developing small molecule modulators of G protein-coupled receptor signaling, and will have the opportunity to work closely with them on support work for the research project. The ideal candidate will not only be innately curious, but also a consummate team player and interested in being a good lab citizen.

• A competitive compensation package, with comprehensive health and welfare benefits.
• A flexible schedule
• One on one mentorship relationship
• Associate Supplement: Annual supplement for eligible postdoctoral Associates to spend on health care, retirement, childcare, or other personal use.

• Work efficiently and cooperatively to assist Postdocs, Graduate Students, and other lab members with experiments.
• Perform a variety of laboratory and investigative procedures - including routine experimental techniques such as electrophoresis, centrifugation, Western blot analysis, PCR, molecular cloning, and tissue culture.
• Express and purify proteins by chromatography and perform crystallography screening.
• Collect, verify, record and compile data and information.
• Participate in laboratory meetings and read literature applicable to the research area.
• Help with lab organization, including accurate documentation and recording/maintenance of large data files.
• Assist with other support duties relating to lab operations as required - such as stocking supplies, cleaning glassware, making common reagents, etc.

• Bachelor's/Master's degree in Biology, Chemistry or a related field.
• Prior experience working in a research laboratory.
• Experience in protein biochemistry including expression, chromatographic purification, and analysis is a strong plus.
• Understanding of basic molecular biology, biochemistry, and related fields.
• Excellent analytical, communication, problem solving, and organizational skills.
• Ability to work both independently and as a team member while engaged in collaborative studies.
• Able to learn complex tasks with instruction, and to use experience to perform a variety of new techniques.
• Actively seeks opportunities to increase skills and expertise.