Vice President, Head of Global Translational Medicine & Research

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals' unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

Genmab is seeking a dynamic, inspirational and science-driven people leader to head our Global Translational Medicine & Research team. This is a unique opportunity to drive translational impact across a diversified pipeline of antibody formats, mechanisms of action, and indications.

The Role

As the Vice President, Head of Translational Medicine & Research, you will lead a global organization of 60+ scientists based in the US and the Netherlands. The team spans a broad spectrum of capabilities (including a translational lab in NL) and plays a pivotal role in shaping translational strategies from discovery through late-stage clinical development.

The Global Head of Translational Medicine & Research (TM&R) will report to the Head of Translational & Quantitative Sciences. You will represent TM&R on the Translational & Quantitative Sciences Leadership Team and be responsible for:

• Providing scientific and strategic direction for the delivery of comprehensive pre-clinical and clinical translational data packages and derived insights, ensuring alignment with organizational goals and regulatory standards
• Advancing biomarker strategies and applying insights to clinical development.
• Driving innovation, scientific excellence, and team development.
• Acting as an ambassador of Genmab science in both internal and external forums.

• Lead global TS TM&R efforts supporting translational strategies, planning, data generation, and insight delivery across all stages of development
• Oversee the development and implementation of biological mechanisms into actionable hypotheses to guide translational strategies that inform trial design, dose optimization, patient selection/stratification, combinations, efficacy monitoring and drive data-driven decision-making
• Conduct recurrent reviews of translational strategies across the portfolio to refine strategic and tactical approaches based on emerging data, medical need, and changes in the treatment landscape.
• Support data contextualization for regulatory submissions, publications, and scientific communications
• Review and approve integration of translational content into regulatory applications including INDs, BLAs, Clinical Study Protocols and Reports, and other regulatory documents (Technical Reports, Regulatory submissions and responses, etc.) Represent TM&R across internal governance bodies and external collaborations
• Champion the application of novel technologies to inform decision-making and enable compound differentiation
• Partner with cross-functional teams to implement AI/ML models for translational insight generation to optimize and accelerate asset development
• Contribute to building foundational knowledge across formats, targets, and safety profiles

• Actively engage with key opinion leaders, technology companies, foundations to advance translational initiatives
• Oversee scientific writing, ensuring high-quality contributions to patents, regulatory documentation, publications, and external presentations across the portfolio
• Present Genmab's translational science at global conferences, expert panels, and in collaboration with academic institutions
• Participate in patient advocacy groups and support initiatives to advance patient engagement

• Strategically plan workforce capabilities and enable a high-performing global team
• Promote scientific and leadership development through targeted training and mentoring
• Drive employee engagement and well-being, leveraging insights from engagement surveys and continuous feedback
• Foster a culture that emphasizes scientific rigor, productivity, and collaboration
• Create a supportive and inclusive workspace that encourages diverse ideas and perspectives

• PhD or MD/PhD in a relevant scientific field (e.g., Immunology, Oncology, Molecular Biology).
• 15-20+ years of drug development experience in biotech/pharma, with demonstrated leadership in translational science or biomarker strategy
• Strong track record of influencing drug development decisions from preclinical to late-stage programs
• Experience leading large, multidisciplinary teams and fostering global collaboration
• Exceptional communication and stakeholder management skills
• Commitment to scientific excellence, strong work ethics, and a passion for translational studies to serve as an inspiration to the team

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

• You are genuinely passionate about our purpose
• You bring precision and excellence to all that you do
• You believe in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with a broad spectrum of backgrounds
• You take pride in enabling the best work of others on the team
• You can grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so!