Scientist II, Small Molecule Process Development and Manufacturing

About This Role

We are seeking a highly motivated and creative individual to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to develop robust processes for the synthesis of a wide range of Small Molecules across various modalities. This Scientist II position provides experiences in early phase to late phase drug development and exposure to the design and development of manufacturing processes for clinical and commercial therapeutics.

Who We Are

We are a team of organic chemists and chemical engineers engaged in the design of innovative processes which supply new medicines to patients. We focus on developing safe, economical, sustainable, and robust processes to support clinical trials and the launch of new medicines across various drug modalities. We are driven by first principles science, data-driven decision-making, and collaborative teamwork.

What You'll Do

• Route scouting, design, and implementation of safe, efficient and robust chemical processes for the synthesis of drug candidates.
• Design and execution of experiments to advance the Biogen portfolio. You will be responsible for analyzing, compiling, and sharing data with project teams.
• Develop the fundamental process knowledge needed to support the transition of chemical and biochemical processes from the laboratory manufacturing partners.
• Collaborate with our Analytical Chemistry, Solid Form, Engineering, and Separations colleagues to develop the knowledge and controls needed for the supply of clinical materials and characterization of the process to support regulatory filings.
• Collaborate with development and manufacturing teams to design and conduct laboratory experiments to optimize and/or characterize the synthesis processes of Small Molecule assets with an emphasis on improvement in process understanding, robustness, and productivity.
• Communicate research results effectively by writing research reports and presenting data in team meetings.
• Engage in the CMC activities including authoring CMC section of INDs.
• Interact with Contract Research Organizations as project needs evolve.
• Initiate innovative research projects to improve fundamental understanding and control of Biogen synthetic processes.

Who You Are

You have a passion for exploring novel scientific concepts and are eager to contribute to the design and development and execution of cutting-edge technologies in the service of delivering drug candidates for clinical trials. Your vision and dedication drive you to push the boundaries of scientific endeavors, ultimately impacting patient lives. You thrive in a collaborative environment where urgency, accountability, inclusion and integrity are shared values.

Required Qualifications

• Ph.D. with 0-3 years of relevant postdoc experience.
• M.S. with 4+ years of relevant experience in pharmaceutical or biotech settings.
• BS with 6+ years of relevant experience in pharmaceutical or biotech settings
• Strong background in the theory and practice of synthetic organic chemistry, including demonstrated understanding of reaction mechanisms, and good problem solving skills
• Experience in route scouting, mechanistic analyses, use of analytical tools (NMR, MS, IR) and purification techniques (chromatography methods).
• Ability to work both independently and collaboratively.
• Good communication skills and a desire to work in a collaborative team environment

Job Level: Management

Additional Information

The base compensation range for this role is: $114,000.00-$152,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Client-provided location(s): Cambridge, MA

Job ID: Biogen-REQ22464

Employment Type: FULL_TIME

Posted: 2026-02-06T23:54:22