Decision Analytics Sr. Manager

About This Role:

In the role of Decision Analytics Senior Manager, you will be a pivotal leader within Biogen's Decision and Quality Analytics Innovation (DQAI) group, which is part of our Development department. As a member of the DQAI team, your primary mission is to drive smarter decisions and measurable impact across our research, development, and medical initiatives. This position requires a blend of strategic acumen and technical proficiency, enabling you to translate complex data into narratives that drive both operational and strategic outcomes. You will oversee strategic direction-setting for decision analytics frameworks, AI/ML-enabled innovations, and enterprise-wide program modeling practices. By partnering with cross-functional R&D teams and external collaborators, you'll play a critical role in shaping enterprise decision science maturity and advancing our analytic capabilities.

What You'll Do:

• Lead end-to-end program modeling efforts for multiple high-impact programs, focusing on assumptions gathering, trade-offs, and ROI analyses.
• Perform scenario planning and "what-if" simulations to understand potential program and portfolio impacts.
• Perform sensitivity analyses and apply strategic-coverage frameworks to unify modeling assumptions across programs, improving governance-ready program narratives and insights.
• Utilize financial data (e.g. discounted cash flow) to evaluate the potential return on drug development projects.
• Institutionalize modeling standards and drive the adoption of strategic-alternatives methodologies and enhance governance decision frameworks.
• Oversee the product roadmap for internal analytics tools, ensuring alignment and scalability.
• Collaborate with IT and data engineering to maintain the R&D analytics infrastructure.
• Architect and integrate advanced AI/ML methodologies into the Decision Science lifecycle.
• Mentor junior staff in quantitative methodologies and decision-making frameworks.
• Engage with functional teams to align program narratives for governance.
• Lead external representation by contributing to peer-reviewed publications and conferences.

Who You Are:

You are a strategic decision analytics leader who brings together deep quantitative expertise and a strong understanding of the drug development landscape. You excel at transforming complex modeling, scenario analysis, and AI/ML-driven insights into clear narratives that guide operational and strategic decisions across R&D. You thrive in environments where innovation, rigor, and cross-functional alignment are essential, and you naturally build trusted partnerships with scientific, clinical, financial, and technical stakeholders. You are both a builder and a connector-advancing enterprise modeling standards, shaping governance-ready decision frameworks, and mentoring others to grow the organization's analytics capability. Your blend of technical proficiency, strategic mindset, and communication strength positions you as a key driver of Biogen's decision science maturity.

Required Skills:

• MS in Data Science, Computer Science, Information Systems, or a related field; advanced degree strongly preferred.
• A minimum of 7 years experience in data science, analytics, or a comparable domain within pharmaceutical R&D or portfolio analytics.
• Expertise in decision analytics, Monte Carlo simulations, pTRS forecasting and quantitative scenario modeling methods.
• High-level proficiency in programming tools (Python/R) and portfolio simulation techniques.
• Proven ability to align cross-functional teams and influence governance decisions.

• Strong problem-solving, critical thinking, and executive-level communication skills.
• Strong communication skills with the ability to translate mathematically rigorous insights into clear recommendations for non-technical
• Familiarity with the drug development process and basic accounting or finance, such as P&Ls and cash flows.
• Recognized for independent problem solving, innovative thinking, and the ability to integrate best practices with hands-on execution in a fast-paced, highly regulated environment.

Job Level: Management

Additional Information

The base compensation range for this role is: $147,000.00-$196,500.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Client-provided location(s): Cambridge, MA

Job ID: Biogen-REQ22044

Employment Type: FULL_TIME

Posted: 2025-12-09T19:14:03