Clinical Development Lead, Rare Autoimmune Nephrology Programs

About This Role

As a Clinical Development Lead for Rare Autoimmune Nephrology Programs at Biogen's West Coast Hub in South San Francisco, you will play a pivotal role in advancing our mission of transforming the lives of patients with severe immune-mediated diseases. Your expertise as a Medical Director (MD) will be vital to the development of novel therapies for rare autoimmune and glomerular kidney diseases. In this dynamic position, you will engage in both early and late-stage clinical programs, emphasizing biopsy-driven and translational science studies. Your contributions will guide the design, execution, and interpretation of trials, in close collaboration with translational scientists, regulatory, and external partners, ensuring impactful study outcomes. You will be part of a vibrant team, driving cross-functional collaboration across research, development, and medical functions, and will help translate mechanistic insights into meaningful patient outcomes that align with Biogen's commitment to innovation and excellence.

What You'll Do

• Lead or support clinical development plans across early- and late-stage programs in rare autoimmune and nephrology indications.
• Provide medical and scientific oversight for biopsy-based, biomarker-driven, and mechanistic studies.
• Partner with Translational Science and Biomarker teams to define scientific hypotheses and exploratory endpoints.
• Support early clinical development efforts, including dose selection and study design.
• Collaborate with Clinical Operations to ensure study feasibility and oversight of trial execution.
• Analyze and interpret translational and clinical data, integrating biomarker and clinical efficacy datasets.
• Draft and oversee completion of clinical study reports, manuscripts, and presentations.
• Contribute to regulatory strategy and interactions with global health authorities.
• Partner with Medical Affairs and Commercial teams for alignment of clinical insights with development strategies.
• Establish relationships with key opinion leaders and academic collaborators.
• Represent Biogen in scientific, regulatory, and industry forums.
• Ensure compliance with GCP and ethical standards across development activities.
• Support due diligence and business development initiatives with clinical expertise.

Who You Are

You are a driven and innovative medical professional with a strong clinical acumen and a passion for translating scientific insights into impactful patient treatments. You thrive in a fast-paced, collaborative environment and are adept at fostering cross-functional relationships. Your strategic mindset and hands-on approach allow you to navigate complex clinical and regulatory landscapes effectively. You communicate with clarity and influence, capable of presenting data to diverse audiences. Your commitment to ethical standards and patient safety is unwavering, and you are motivated by the opportunity to make a significant impact in the field of nephrology and autoimmune diseases.

Required Skills

• MD or equivalent degree, with board certification in nephrology, immunology, rheumatology, or a related field.
• 3+ years of clinical development experience in the pharmaceutical or biotechnology industry.
• Experience in biopsy-based or translational studies and biomarker data interpretation.
• Strong understanding of clinical trial design, including adaptive and biomarker-enriched approaches.
• Experience with early-phase (Phase 1-2a) trials, including first-in-human studies.
• Knowledge of regulatory requirements and participation in global health authority interactions.
• Ability to interpret complex biological and clinical data into development strategies.
• Exceptional communication and leadership skills for matrixed organizational influence.
• Strategic and creative mindset suitable for a fast-paced environment.
• Willingness to travel (10-20%) domestically and internationally.

Preferred Skills

• Experience with mechanistic studies in early-phase trials.
• Proven track record of establishing relationships with key opinion leaders.
• Familiarity with startup-like environments.

*LI-RD8

Job Level: Management

Additional Information

The base compensation range for this role is: $202,000.00-$278,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Client-provided location(s): Flexible / Remote

Job ID: Biogen-REQ22060

Employment Type: FULL_TIME

Posted: 2025-12-04T19:13:51