It's easy to feel down about a career setback—and all of us have them. But, as a reminder that where we are today doesn't dictate where we can go from here, we pulled together a list of amazing entrepreneurs who've experienced hardships that might surprise you.

1. Ursula Burns, CEO of Xerox

Fortune Most Powerful Women 2012

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2. Larry Ellison, CEO and Co-Founder of Oracle

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3. Guy Laliberte, Founder and CEO of Cirque Du Soleil

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Image courtesy of Wikipedia

4. Li Ka-shing, Chairman of Hutchison Whampoa Limited and Cheung Kong Holdings and the Richest Person in Greater China

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5. Lloyd Blankfein, CEO and Chairman of Goldman Sachs

Fortune Most Powerful Women 2012

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6. Oprah Winfrey, Media Mogul and Entrepreneur

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 Image courtesy of Wikipedia

7. Steve Jobs, Co-Founder, Chairman, and CEO of Apple

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 Image courtesy of Ben Stanfield

Sources: Businessweek, Wikipedia, Huffington Post, and Discovery.