Principal Enterprise Applications Manager, Mckesson

Infosys is seeking a Principal Enterprise Applications Manager

As a Principal Enterprise Applications SAP consultant, you will be a expert contributing to different phases of the consulting lifecycle. You will be intensely involved in business process consulting; you will define the problem, propose and create the solution. You will also play an important role in the development, configuration and deployment of the overall solution. You will guide teams on project processes, deliverables and contribute to the proposal development, client training and internal capability building and help detail the project scope. You will have the opportunity to shape value-adding consulting solutions that enable our clients to meet the changing needs of the global landscape.

Basic Qualifications

• Bachelor's degree or foreign equivalent required from an accredited institution. Will also consider three years of progressive experience in the specialty in lieu of every year of education.
• At least 11 years of experience with Information Technology.
• This position may require travel and/or relocation.
• Candidates authorized to work for any employer in the United States without employer-based visa sponsorship are welcome to apply. Infosys is unable to provide immigration sponsorship for this role at this time

Preferred Qualifications:

• SAP Project Manager with deep expertise leading brownfield conversions to SAP S/4HANA within regulated, pharma/life sciences environments. This role will own end-to-end program delivery across business functions (Finance, Supply Chain, Manufacturing, Quality, Commercial) while ensuring strict compliance with GxP/CSV, SOX, FDA/UDI, and Pharma Quality standards.
• In addition, this role includes Cutover Management leadership, responsible for strategy, planning, execution, and governance of all cutover activities across business, IT, data, technical, and manufacturing sites.
• The ideal candidate has hands-on delivery of at least one S/4HANA brownfield implementation, strong SAP Activate knowledge, proven system integrator management experience, and extensive execution of cutover cycles, mock conversions, and downtime orchestration in complex global landscapes.
• Program & Delivery Management
• Lead the end-to-end S/4HANA Brownfield Conversion lifecycle: discovery → planning → build → testing → cutover → hypercare → stabilization.
• Own program governance: scope, budget, schedule, RAID, dependencies, KPIs, and executive reporting.
• Manage SAP Activate across Discover, Prepare, Explore, Realize, Deploy, Run-including hybrid Agile/Wave-based delivery.
• Facilitate cross-functional governance forums, steering committees, and risk/escalation trajectories.
• Brownfield-Specific Execution
• Drive SAP Readiness Check, Simplification Item evaluation, Custom Code Analysis, sizing, and compatibility validation.
• Oversee technical conversion with BASIS & infra: SUM/DMO, Maintenance Planner, Stack XML generation, dual maintenance, downtime reduction planning.
• Lead custom code remediation, Fiori activation, and Business Partner (BP) conversion.
• Define and manage conversion strategy for key data objects: FI docs, open items, materials, batch/serial, BP, etc.
• Coordinate multiple mock conversions, dry runs, and system preparation activities.
• Cutover Management (Expanded Section for Pharma S/4HANA Brownfield)
• Cutover Strategy & Governance
• Lead the complete Cutover lifecycle for the S/4HANA brownfield program across all business functions and global sites.
• Develop the comprehensive Cutover Strategy, aligned with pharma regulatory, GMP, and validated system requirements.
• Establish cutover governance: checkpoints, approvals, command center structure, and communication flow.
• Cutover Planning
• Build and maintain a detailed Integrated Cutover Plan covering:
• Technical conversion activities
• Functional steps
• Business operations freeze windows
• Regulatory and validation checkpoints
• MES/WMS/MES/LIMS/PLM and serialization integration tasks
• Plan for downtime minimization and coordinate downtime playbooks for manufacturing and distribution environments.
• Mock Cutover & Dress Rehearsals
• Lead multiple Mock Cutovers, evaluating:
• system conversion duration
• data readiness
• dependencies & integration stability
• business process continuity readiness
• Identify bottlenecks and drive performance tuning with BASIS, data, and infra teams.
• Pharma/Regulated Process Focus
• Ensure GxP & CSV-aligned cutover documentation including:
• validated procedures for transitions
• audit trail controls
• change control approvals
• batch-impact assessments
• Align with 21 CFR Part 11, UDI, ISO 13485, and internal QMS procedures.
• Data Migration & Conversion Readiness
• Manage data migration workstreams, ensuring:
• cleansing
• mapping
• validation
• mock conversion testing
• reconciliation & signoffs
• Lead cutover-related data validation with QA, manufacturing, supply chain, and finance.
• Cutover Command Center Execution
• Run the cutover command center during go-live:
• Coordinate 24×7 execution teams
• Manage issue triage, escalation, and resolution
• Ensure adherence to freeze periods and validation controls
• Communicate milestone progress to leadership
• Go-Live & Hypercare Cutover Support
• Ensure deployment readiness and final cutover checklist signoff.
• Lead the transition into hypercare including stab

The job entails sitting as well as working at a computer for extended periods of time. Should be able to communicate by telephone, email or face to face.

Client-provided location(s): Irving, TX

Job ID: Infosys-153946BR

Employment Type: OTHER

Posted: 2026-09-23T19:25:25