Manufacturing Associate II & III - Cell Culture (Nights)

This requisition represents multiple open positions in our manufacturing organization. The Talent Acquisition team continually assesses all applicants that apply through this posting and will reach out to prospective candidates to discuss current and future opportunities.

About This Role

Our factories run 24/7 operations. Our manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation.

• Shift Details: This role follows a 2-2-3 calendar rotation on nights (6:00 PM - 6:00 AM ET)
• Internal Shift Details: Red Nights rotating schedule

Our Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations - each playing a critical role in delivering our therapies to the patients who need them.

Our teams are organized by the steps in the biomanufacturing process that they operate in; including - Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. Manufacturing Associates perform these critical steps in a clean environment governed by Current Good Manufacturing Practices (cGMP).

This role's primary focus is on Upstream Cell Culture operations.

What You'll Do

• Perform inoculation thaws, splits, and pools using aseptic technique with WAVE bags and ITV cans
• Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV
• Standardize and calibrate pH and DO probes during bioreactor preparation
• Perform inoculation of bioreactors across multiple scales
• Support cell growth operations, including media feeds and process additions
• Conduct routine sampling and in-process testing to monitor product quality
• Standardize and maintain laboratory and manufacturing equipment, including:
  • Vi-Cell Blu/XR
  • Osmometer
  • pH meters
  • RapidPoint BGA
  • Conductivity meters
  • Biosafety cabinets
  • Small-scale centrifuges
• Accurately document activities in accordance with cGMP and SOP requirements
• Maintain a clean, safe, and compliant manufacturing environment
• Collaborate cross-functionally with Manufacturing, MSAT, Quality, and Engineering teams

Who You Are

You're driven by a mission to save lives and bring a deep sense of purpose to the work you do. Biomanufacturing is complex, and you thrive in fast-paced environments where learning agility, problem-solving, and adaptability are essential.

Required Skills for a Manufacturing Associate II: $23.56 - $30.77 Pay Range

• The following combination of academic and/or relevant experience may be considered:
  • Bachelor's degree from an accredited college or university, STEM preferred and 0+ years of related experience
  • A BioWorks Certificate or associate's degree, STEM preferred and 0+ years of related experience
  • A High School Diploma (or equivalent) and at minimum of 1 year of related experience
• Previous experience in a cGMP environment
• Ability to follow SOPs and work effectively on shift schedules if required
• Demonstrated documentation and data integrity skills
• Understanding of aseptic technique and cleanroom practices is preferred

Required Skills for a Manufacturing Associate III: $25.96 - $34.13 Pay Range

• The following combination of academic and/or relevant experience may be considered:
  • Bachelor's degree from an accredited college or university, STEM preferred and 2+ years of related experience
  • A BioWorks Certificate or associate's degree, STEM preferred and 2.5+ years of related experience
  • A High School Diploma (or equivalent) and at minimum of 3 years of related experience
• Previous experience in a cGMP environment
• Ability to follow SOPs and work effectively on shift schedules if required
• Demonstrated documentation and data integrity skills
• Knowledge of aseptic technique and cleanroom practices
• Exposure to Delta V, Syncade, or similar systems
• Experience performing bioreactor preparation, inoculation, and monitoring is preferred
• Hands-on experience with mammalian cell culture operations is preferred

Job Level: Entry Level

Additional Information

The base compensation range for this role is: $23.56-$34.13

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Client-provided location(s): Research Triangle Park, NC

Job ID: Biogen-REQ22717

Employment Type: FULL_TIME

Posted: 2026-02-27T23:58:39