CLINICAL GENOMICS ANALYST, TUMOR PROFILING

Overview

To be part of our organization, every employee should understand and share in the YNHHS Vision, support our Mission, and live our Values. These values—integrity, patient-centered, respect, accountability, and compassion—must guide what we do, as individuals and professionals, every day.

JOB SUMMARY

The Analyst will write interpretive clinical reports for the Laboratory's next-generation sequencing cancer-related tests. The Analyst will assess genetic variants and therapeutic approaches in the context of the patients' complete molecular profile and disease to deliver clinical reports in a timely CLIA/CAP compliant manner. The Analyst will present the reports to the Pathologist on service who will review, revise as needed and finalize in the medical record. The Analyst will curate the knowledge base by collecting and integrating data from scientific literature and databases and compiling the data in a format compatible with clinical reporting.

EEO/AA/Disability/Veteran

Responsibilities

  • 1. Writes interpretive clinical reports relevant to the patients' molecular profile in a CLIA/CAP compliant manner.
    • 1.1 Analyzes all sequencing data, including alignment, variant calling, copy number variation and annotation, including germline comparison, according to assay performance characteristics in concert with the bioinformaticists.
  • 2. Curates knowledge base.
    • 2.1 Analyzes scientific literature and databases related to cancer biology, somatic variants and related therapeutic clinical efficacy, including clinical trials.
  • 3. Participates in activities that demonstrate commitment to quality improvement.
    • 3.1 Works with technical team, bioinformaticists and IT to enhance workflow efficiency and robustness.
  • 4. Participates in activities that demonstrate commitment to competency, career growth and professionalism.
    • 4.1 Has excellent communication skills. Effectively communicates with staff and physicians in a clear and concise manner. Encourages and elicits feedback from staff on work process improvement. Effectively communicates issues to the Laboratory Manager and Director.

Qualifications

EDUCATION

 

PhD in genetics, genomics, molecular biology, cancer biology or an equivalent.

 

EXPERIENCE

 

Minimum three years experience in molecular genetic/genomic technologies including next generation sequencing and interpretive strategies. Experience with bioinformatic tools and databases (NCBI, COSMIC, Ensembl, IGV).

 

SPECIAL SKILLS

 

High level of professional maturity, ability to consistently meet deadlines, strong attention to detail and focus on quality. Ability to quickly assess, interpret, integrate and assemble relevant medical and scientific literature. Demonstrated knowledge of cancer biology, oncology, targeted therapies/pharmacology a plus.

 


See Inside the Office of Yale New Haven Hospital

Yale New Haven Hospital provides diverse comprehensive care in over 100 medical specialties. As the primary teaching hospital of the Yale School of Medicine, YNHH provides around-the-clock coverage and insightful, research-supported patient care. In addition to providing quality medical care to patients and families, Yale New Haven Hospital is the second largest employer in the New Haven area, with more than 12,000 employees.


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