Research Scientist I - EX
The Ben Towne Center for Childhood Cancer Research (BTCCCR) at Seattle Children's Research Institute (SCRI) seeks to develop innovative new cellular therapies and translate these advances to groundbreaking clinical trials for children with the most aggressive forms of cancer. We are seeking bright, enthusiastic, highly-motivated and experienced molecular and/or cellular biologists to join the Jensen Lab at BTCCCR. This position contributes to a team focused on translating tumor immunotherapy from the bench into pediatric patients with cancer. We look for people who are inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of our research team culture.
The primary purpose of this position is the development and testing of chimeric antigen receptors (CARs) for use as clinical therapies. Under the direction of a senior research scientist, the successful candidate will use her/his established in vivo experience to design and implement in vivo experiments aimed to examine the antitumor activity of CAR T-cells. The candidate will perform mammalian cell culture, multiparameter flow analysis, and multiple in vivo tumor models.
The ideal candidate will have significant work experience in immunology, tissue culture, flow cytometry, and mouse models. Of utmost importance, the candidate will have experience in multiple basic mouse procedures and animal husbandry. The candidate will be extensively involved in implementing new strategies, generating data, analyzing results and preparing reports, in support of funded research studies. She/he must have critical thinking abilities, be able to prioritize and perform multiple tasks in a dynamic environment, meet deadlines, and must have excellent written, verbal and interpersonal communication skills, to ensure successful project completion and teamwork. The candidate will be required to participate and present data in weekly lab meetings and maintain up-to-date and well-organized electronic lab notebook.
Minimum Education and Experience: (Identify only education requirements that are legally defensible - e.g., an attorney needs a Juris Doctor)
- Bachelor's Degree in biology, microbiology, immunology, molecular biology or biochemistry.
- At least one (1) year of laboratory research experience
- At least one (1) years experience with mouse models
- Experience in basic mouse procedures such as peritoneal injections, tail vein injections, retro orbital eye bleeds, tissue harvesting, etc. may be preferred
- Research experience in biochemistry, molecular biology, and tissue culture techniques may be preferred.
Knowledge, Skills, and Abilities:
- Knowledge of basic laboratory techniques
- Knowledge of animal welfare regulations and guidances
- Knowledge of appropriate computer software, installation and upgrades related to area of research, and proficiency using - MS Office (Outlook, Word, Excel & Access)
- Knowledge of Good Laboratory Practice (GLP) and understanding of safe lab practices and BSL requirements
- Good data collection, reduction and summary skills
- Good written communication skills
- Good communication/interpersonal skills
- Effective organizational skills
- Good analytical and problem-solving skills
- Able to effective prioritize work assignments and address competing demands of multiple projects
- Able to establish and maintain effective working relationships with a variety of people
- Able to follow both verbal and written instructions
- Able to work a flexible work schedule to meet the needs of the laboratory
- Able to move around different work sites to perform job duties and to use specialized equipment as required by area of research
- Significant individual initiative and motivation to research and learn scientific methods and knowledge in their project area
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