Fellow - PhD

Job Description:

Post-Doctoral Positions In T Cell Immunity and Cancer Immunotherapy

Laboratories of Dr. Surojit Sarkar and Dr. Vandana Kalia, at the Seattle Children's Research Institute (SCRI, Seattle, WA), are seeking highly motivated and productive post-doctoral fellows to join our research groups. We are pursuing fundamental research on the mechanisms underlying T cell immunity to acute and chronic pathogens, and cancer. Our research program currently lies at the translational interface of immunology aimed at elucidating the mechanistic basis of immunological memory and T cell exhaustion, functional engineering of CAR T cells and discovery of novel immunotherapies to cancer. Located in the heart of the world-class biomedical research cluster in Seattle, the Sarkar and Kalia laboratories have existing collaborations and synergies with University of Washington School of Medicine, Fred Hutchinson Cancer Research Center, Benaroya Research Institute and Institute for Systems Biology. Interested candidates are encouraged to send an email to Dr. Sarkar and Dr. Kalia with questions.

For more information on past publications and the research program, please see:

Sarkar Google Scholar

Kalia Google Scholar

Requirements

Essential requirements:

  • A recent PhD or MD/PhD in Immunology or other closely related field with at least one published first-authored peer-reviewed manuscript from graduate research work.
  • New doctoral graduate or post-graduate experience of 0-3 years working on a T cell immunology related project.
  • Fundamental expertise in T cell immunology concepts and experimentation.
  • Experience working with mouse colony, in vivo murine experimentation and techniques.
  • Expertise with core cellular immunology techniques including multi-color flow cytometry, in vitro T cell stimulation assays, and mammalian cell culture.
  • Proficiency with molecular techniques such as DNA/RNA isolation, cloning, PCR, quantitative RT-PCR, and retroviral transduction

Preferred skills:

  • Experience with bioinformatics tools for large data set analysis.
  • Prior experience with tumor immunology in murine models
  • Experience using Seahorse with whole cell metabolism-related assays and metabolomics.
  • Prior grant-writing experience and evidence of procuring any competitive funding (amount not important)

Requirements:

Required Education/Experience: - PhD in specialty area from an accredited university training program - Experience using basic research techniques of specialty area Required Credentials: N/A

Preferred: - Previous experience conducting research in the pediatric arena - Experience in protocol and manuscript development and in grant writing.


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