Senior Scientist, Disease Genetics - Population Analytics

    • Spring House, PA

Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting a Senior Scientist, Disease Genetics in our Population Analytics group, to be located at our Spring House, Pennsylvania campus in the United States.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.

We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal.Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

Janssen Pharma R&D seeks an innovative scientist with expertise in creatively applying quantitative analysis to large-scale population-based studies as well as real-world data to advance our pharmaceutical and/or biomedical research, drug discovery and development agenda. We seek an individual with strong training and experience in applied quantitative methods and a track record of scholarship. Candidates should possess excellent communication skills as well as broad biological interests that will enable them to effectively interact with laboratory-based scientists of our Therapeutic Areas.

He/she will be a member of the Population Analytics team, which resides in Computational Sciences within the Discovery Sciences organization. The Population Analytics team aims to bring together researchers within and outside of Janssen with expertise in human disease genetics, statistical genetics and genetic epidemiology, computer/computational science, and high-performance computing. Its mission is to support longitudinal, population-based studies to increase our understanding of pathologies and contribute to Janssen's goals of preventing, intercepting, and treating human diseases. This team is responsible for the integration, analysis and interpretation of data collected on various cohorts and across geographical/time scales. They work on deciphering causal factors such as genes, the environment and an individual's lifestyle with the aim to facilitate the discovery of novel targets, biomarkers, biological mechanisms and pathways implicated in diseases. The team's goal is to use biomedical data to build a best-in-class target identification and validation engine (TIDVALE) to feed our discovery pipeline.

Role & responsibilities:

  • Provide scientific expertise for hypothesis generation, study design, and advanced statistical methods in collaboration with scientists within and outside the Population Analytics team. Provide design and analysis consultation for questions of interest to our Therapeutic Areas and facilitate interactions between colleagues across the organization.
  • Develop or apply a wide variety of statistical genetics/genomics methods to integrate and analyze phenomic and genomic data from large population cohorts such as the UK Biobank (eg. demographics, clinical information from electronic health records, imaging/biosensor, WES, WGS, and other omics data), and design targeted studies to identify or validate potential therapeutic targets and biomarkers.
  • Mentor, train, and support other scientists in the group as needed.
  • Perform and publish high-quality research that is relevant to the mission of the organization; effectively communicate data and results to our stakeholders within and outside of J&J and work effectively with colleagues across J&J sectors.

  • A M.D. and/or Ph.D. in statistical genetics, genetic epidemiology, biostatistics, statistics, or computational sciences with deep expertise in genomic analysis is required.
  • A minimum of 5 years post-graduate experience analyzing large-scale human genomics data is required.
  • Strong programming and computational skills and demonstrated ability to work with a group of scientists to deliver on objectives in defined timelines, are required.
  • Independent, self-motivated, innovative, and able to excel in a goal-oriented, multifaceted and fast-moving team environment are required.
  • Outstanding communication, organizational and leadership skills, with a successful track record of publication and collaboration with cross-functional scientific teams are required.
  • Experience with drug discovery and development practices and project support in a large pharmaceutical setting is preferred.
  • The role will require up to 10% domestic/international travel. The role will be based in our Spring House Pennsylvania campus in the United States.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location
United States-Pennsylvania-Spring House-
Janssen Research & Development, LLC (6084)
Job Function
Requisition ID

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