Howard Hughes Medical Institute

Research Technician - Meyer Lab

3+ months agoEmeryville, CA

Primary Work Address: 2033 Valley Life Sciences Building, Berkeley, CA, 94720-3140

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We are currently looking for an enthusiastic, scientifically curious Research Technician to work in the lab of Dr. Barbara Meyer at the University of California, Berkeley in Berkeley, California. The Meyer laboratory carries out pioneering research on the mechanisms of cell-fate determination, genome editing, the role of chromosome structure and chromatin modification in gene regulation, and the molecular evolution of chromosome-wide mechanisms of gene control in the nematode C. elegans, with an emphasis on X-chromosome dosage compensation and sex determination. Tools used include genetics, genomics, molecular biology, advanced imaging, and structural studies including X-ray crystallography. More information about the Meyer lab can be found here: http://mcb.berkeley.edu/labs/meyer/index.html

The ideal candidate is an organized, detail-oriented individual who will be responsible for working with Ph.D. scientists to understand key areas of developmental gene regulation and cell-fate specification, including chromosome structure and its relationship to chromatin modification and gene expression during embryo development.

Of particular interest to the lab are candidates with strong skills in molecular biology. Experience in imaging and computational analysis of big data is a definite plus. Previous research technicians from the lab have been co-authors on major scientific publications and have gained acceptance to prestigious graduate and/or medical programs.

Principal Responsibilities:


  • Perform experiments involving molecular biology, genetics, genomics, and imaging in combination with genome editing for ongoing research projects investigating cell-fate determination and chromosome-wide regulation of gene expression C. elegans.

  • Assist in computational analysis of big data generated through imaging and genomics experiments. Prior knowledge in image analysis and/or genomics data analysis will be a big plus.


Qualifications
Education

  • A bachelor's degree in biology or a related discipline is required.


Experience

  • 1-2 years of previous hands-on laboratory experience in molecular biology is required along with a strong understanding of molecular genetics. Significant laboratory experience obtained during undergraduate studies is acceptable and will be considered.

  • Previous experience with C. elegans genetics would be a plus.

  • Previous experience with advanced imaging techniques would be a plus.

  • Previous experience with computational data analysis and coding capability in any language (preferably in Python and/or R) would be a plus.


Knowledge, Skills, and Abilities

  • Superior verbal and written communication skills.

  • Superior organizational skills, prioritization skills, time management skills, and meticulous attention to detail.

  • Proficient skills in data analysis using Python and/R.

  • Ability to work well both independently and as a member of a team.

  • Ability to follow instruction with an eagerness to learn, grow professionally, and be
    mentored.

  • Ability to interact positively with all levels of staff.

  • Ability to work efficiently, be adaptable, and be self-motivated.


Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

HHMI is an Equal Opportunity Employer

Job ID: HHMI-R-293