Postdoctoral Associate - Lefkowitz Lab

    • Durham, NC

Primary Work Address: MSRB 1, Suite 301, Research Drive, Durham, NC, 27710

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We are currently seeking a forward-thinking, inventive and results driven Postdoctoral Associate within the lab of Dr. Robert Lefkowitz at Duke University in Durham, NC. The Lefkowitz lab studies the molecular and regulatory properties of G protein-coupled receptors (GPCRs), also known as seven transmembrane spanning receptors (7TMRs). Current work in the lab focuses on understanding how GPCR cell signaling, by biased or unbiased ligands, is mediated through GPCRs and their transducers, the G proteins and β-arrestins. The lab utilizes techniques ranging from biophysics to pharmacology to cell biology to in vivo animal disease models - and more information on their research can be found on their website.

We are targeting candidates who have a strong background in a variety of biochemical, biophysical, and cell biological techniques. The lab thrives on developing novel solutions to challenging problems - so we need someone who isn't afraid to both think outside the box and challenge the status quo. We feel science moves forward best when you aren't afraid to question everything and embrace creative experimental approaches - and we want team members who are as enthusiastic about that approach as they are about our science.

General Qualifications:

  • PhD within the last 2 years
    • Background in structural biology strongly preferred
  • Effective communication skills, self-motivated, and a strong work ethic
  • Ability to work both independently and in a collaborative group environment
  • Experience with either X-Ray Crystallography or Cryo-Electron Microscopy required


Applicants should submit both their curriculum vitae and a detailed statement on how their experience and interests relate to our work.

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:
This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.

HHMI is an Equal Opportunity Employer


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