VP - Clinical Development - Cancer Epigenetics (Oncology)

    • Collegeville, PA

Site Name: USA - Pennsylvania - Upper Providence
Posted Date: May 20 2020

Are you a pharmaceutical physician executive with the ability to develop a competitive, long term strategic vision for a cancer epigenetics portfolio? If you seek to join a company committed to focus on Oncology R & D, then this VP position at GSK may be ideal for you to explore.

GSK Oncology is in an exciting and expanding transformation in response to a significant increase in GSK's early and late stage medicine development volume in Oncology. This transformation has resulted in a rapidly expanding portfolio of clinical development assets requiring both strong scientific and clinical development expertise and leadership skills for influencing internal and external stakeholders. In that regard, GSK seeks four (4) new Vice Presidents to support each of Cancer Epigenetics, Cell Therapy, Immuno-Oncology and Oncology Genetic Medicine. These positions report to the SVP - Oncology Clinical Development.

GSK Oncology R&D is focused on building industry-leading portfolios in four cutting-edge areas of science:
•Immuno-Oncology : using the human immune system to treat cancer
• Cell/Gene Therapy: engineering human T-cells to target cancer
•Cancer Epigenetics: modulating the gene-regulatory system of the epigenome to exert anti-cancer effects
Synthetic Lethality: targeting two mechanisms at the same time which together, but not alone, have substantial effects against cancer

For more Information on GSK Oncology, please visit: https://us.gsk.com/en-us/careers/a-career-in-oncology/

The VP-Development -Cancer Epigenetics will be accountable for all aspects related to the development of the clinical assets in the Cancer Epigenetics portfolio. The VP-Development Cancer Epigenetics will be responsible for managing physicians and clinical scientist assigned to the clinical development team(s). As a key responsibility, the VP-Development will supervise the design and implementation of the clinical development strategy and plan for the Cancer Epigenetics portfolio, including the strategic positioning of individual assets, the effective allocation of development resources, and the timely and successful execution of clinical trials.

This role of VP-Development requires an experienced, cross-matrix senior leader capable of implementing and executing an integrated clinical strategy in support of the successful clinical development, regulatory filing and initial market launch of a growing portfolio of innovative and transformational Cancer Epigenetics agents


• Responsible for the end-to-end clinical development of the Cancer Epigenetics portfolio from First Time In Human (FTIH) clinical trials through Proof-of-Concept (POC) studies, and pivotal trials to regulatory approval and initial market launch
• Responsible for providing medical guidance for pre-clinical research activities from drug candidate Selection through to POC.
• Responsible for building and maintenance of effective business partnerships within GSK Oncology R &D and with external partners and collaborators.
• To lead intra- and inter-departmental teams, matrix-manage a cross-functional teams
Problem Solving & Innovation

  • The role of VP requires exceptional problem solving skills and innovative thinking in order to anticipate emerging therapeutic standards in Oncology and to successfully position the GSK portfolio of Cancer Epigenetic compounds in an increasingly competitive pharmaceutical business environment
  • Interaction
  • The role of VP requires strong interpersonal and communication skills in order to successfully promote the strategy guiding the clinical development of the Immuno-Oncology portfolio within the GSK organization and to generate interest in the international, scientific and clinical Oncology community for emerging drug development programs and transformational, new therapies.

Multi Cultural
  • The role of VP requires an in depth understanding of multi-cultural responsibilities in order to organize, motivate, and lead multi-functional teams of scientific and clinical experts located in different research centers within the global GSK R&D organization

  • The VP will play a central role within the Oncology TA as he will be responsible to enforce the clinical development strategy for the Immuno-Oncology portfolio and ensure the allocation of the necessary resources within the GSK R&D budget to development and launch transformational new medicines


Why you?

Basic Qualifications:
  • Medical Degree with qualifications in a related medical specialty
  • At least 5 years clinical development experience in the pharmaceutical industry
  • Experience in early and late phase drug development and translational medicine
  • Demonstrated track record of successfully developing and executing Clinical Development Plans
  • Experience in the successful filing, approval and initial launch of a novel therapy is a plus
  • Experience with clinical and translational investigation of cancer epigenetics modifiers is an advantage

Preferred Qualifications:
  • Medical degree with sub-specialty qualifications in Oncology

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture.
These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk, governance and control, managing ambiguity and paradox.
  • Managing individual performance.
  • Creating a performance culture and driving results, prioritisation, execution, delivering performance.
  • Setting strategic direction and leading on-going organisational transformation.
  • Building a resilient organisation.
  • Building strong relationships and collaboration in service of common goals, engaging the organisation and building trusted external networks for mutual benefit.
  • Managing P&L and capital allocation.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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