USMA Therapy Area Head -Oncology
- Philadelphia, PA
Site Name: Philadelphia Navy Yard
Posted Date: Feb 25 2019
GlaxoSmithKline (GSK) is science-led global healthcare company with a special purpose: to help people do more, feel better, live longer. GSK has three world-leading businesses that research, develop and manufacture innovative pharmaceutical medicines, vaccines and consumer products. Our goal is to be one of the world's most innovative, best performing and trusted healthcare companies.
GSK's powerful combination of skills and resources provides a platform for delivering strong growth and responding quickly to the rapidly changing global healthcare environment. We are focused around three core business: Consumer Healthcare, Pharmaceuticals and Vaccines. With global commercial infrastructure and functional support, international supply networks and innovative R&D, GSK has a global commercial presence in more than 150 markets, a network of 84 manufacturing sites in 36 countries and large R&D centers in the UK, US, Belgium and China. The United States is the single largest market for GlaxoSmithKline.
A more integrated, competitive Pharmaceuticals business is foreseen by significantly strengthening the existing partnership between R&D and commercial. GSK announced its commitment to prioritizing its biggest revenue driver, the pharmaceutical business, recognizing the heart of that business is pharma R&D. Going forward, four key areas will benefit from 80 percent of the R&D budget; respiratory, HIV/infectious diseases, immuno-inflammation and oncology.
Leading GSK in this new era is Emma Walmsley who was appointed CEO in 2017. Several significant leadership appointments including Hal Barron, Chief Scientific Officer and President of R&D; and Luke Miels, President, Global Pharmaceuticals have been made. Both are highly respected leaders with a track record of bringing new medicines to market.
As a global healthcare company, GSK takes on some of the world's biggest healthcare challenges. The biggest contribution we can make to society is to innovate and widen access to new medicines, vaccines and consumer healthcare products. We continue to be committed to develop medicines to support fighting cancer. Over the last few years our R&D team has been using 'next generation' technology platforms to increase understanding of disease mechanisms, which will help us deliver significant medical advances to cancer patients.
Your role will be at the forefront of GSK's re-emergence in discovering and providing cutting edge Immuno-Oncology treatments. Our leading Oncology asset is GSK2857916/GSK'916, an anti B-cell maturation agent (BCMA) monoclonal antibody-drug conjugate. This is a first in class antibody drug conjugate that has a four-fold mechanism of action with evidence of high efficacy in a precisely defined group of Multiple Myeloma patients. BCMA has recently been granted Breakthrough Therapy Designation from the FDA and as such we are looking to launch the asset at speed.
Reporting to Karin Rosen, M.D., Ph.D., the USMA Therapy Area Head ('TAH') Oncology is an executive level position established to ensure that deep medical and scientific expertise is in place throughout Oncology and provide Medical Affairs oversight and governance within the US is in place and adhered to. The TAH will provide the vision and leadership to drive the medical strategies for the therapeutic area and Medical Affairs Excellence, in alignment with the Franchise and Commercial organization. Additionally, the TAH will provide oversight and strategic direction for all medical resources supporting this unit, including the US Field-based Medical Organization. As the senior leadership for the Oncology area, accountability for providing the vision and leadership to ensure Medical Affairs excellence in Oncology within the US Region is imperative. The TAH will be an expert on the external HCP environment, emerging therapeutic trends, collection and characterization of external insights. S/he will be accountable for the development of specific, commercially aligned medical affairs plans to help define the value proposition of our medicines, including operationalizing regional evidence generation as appropriate, as well as the appropriate external communication of our data to external HCPs. The incumbent will ensure that all medical affairs activities are conducted with the utmost integrity.
The USMA TAH for Oncology is the medical partner to the US Business Unit Head and the Franchise Medical Head, along with colleagues in clinical R&D. S/he will ensure the TA medical voice of customer and market is deeply understood, synthesized across multiple customer segments into medical insights and clearly translated into appropriate actions to enable appropriate use of our medicines for patients in US. S/he will also ensure that medical insights are communicated on a regular basis to key partners (Franchise, Development & Discovery, and Commercial) in a strategic and action-oriented way.
It is necessary to ensure the highest scientific integrity across the therapeutic areas. In addition (s) he will stay abreast of current product issues and address / make recommendations and provide medical expertise on a wide range of topics. This role is especially important in light of GSK's announcement that we will no longer pay external HCPs to speak on our behalf. With this announcement, external education will be the responsibility largely of Medical Affairs and the incumbent will be accountable for ensuring that the right people with the right capabilities are in place and trained for this. It will be important to provide a credible and deeply scientific external voice for GSK and to ensure rapid and thorough responses to product issues and, more importantly, to anticipate and mitigate problems before they occur. It is also important to have the broad perspective across the portfolio and to share learnings and best practices as appropriate to deliver medicines of value to the patient.
It will be essential for the TAH to be able to ensure talent and leadership in the medical teams and deep understanding of the customer, competitive environment and the marketplace. Assurance of the alignment and partnership with Safety and Regulatory, Compliance and Medical Governance, as well as the legal environment within the US for the oncology area is critical.
This TAH will sit on the US Medical Leadership team (MALT) and appropriate commercial leadership teams. (S)he will be expected to participate in setting the direction for GSK for the therapeutic area with NA, proactively identifying and acting on local market pressures and trends in patient care and treatment. As a key leader in US Medical Affairs, this role will also be expected to contribute to the overall management of, providing input and direction for the overall strategy and management of the organization.
- Accountable for oversight and coordination of the Oncology Medical team, effectively managing resources and staff to successfully deliver launch and growth of key assets in the oncology portfolio.
- Ensure alignment between US Medical and R&D/Oncology Therapy Area around medicines vision, payer insights, development strategy and commercial ambition in US market for key assets.
- Provide strategic direction and end to end excellence for early assets to help shape the profile of products at a very early stage.
- Ensure balanced and robust scientific communication with the US external KOL and scientific/medical community around the value of GSK Oncology science and medicines. In particular, the focus should be on rebuilding a strong network of scientific experts to highlight our presence in the external oncology medical community.
- Attract and grow talent in key US medical roles and build organizational capability.
- Act as a key strategic partner to the US Oncology Business Unit leader, ensuring medically sound promotional positioning, clear and relevant promotional and medical materials, and strategically aligned commercial and medical plans. Provide support and guidance to key asset and product decisions by taking into consideration specific commercial contexts and input from R&D.
- Anticipates the changing healthcare, regulatory & competitive environment throughout the portfolio lifespan.
- Ensure medical governance principles and processes are adhered to within and beyond the area.
- Provide a key input on (1) ensuring Phase III R&D studies meet the regulatory, clinical, patient and payer needs and (2) have accountability for all related Phase IIIb/IV studies.
- Lead the successful implementation of all US medical deliverables, tailored to regional needs as appropriate.
- Provide consolidated medical input to US brand strategies and campaigns; driving their implementation through the networks.
- Facilitate world class launches of a / all new assets in the TA.
- Leverage patient, physician and payer insights in the robust assessment of market access/reimbursement requirements for pipeline asset(s) ensuring effective medical input from the US into the Medicine Vision process.
- Ensure appropriate medical governance oversight of all US medical and commercial deliverables.
- Lead the management of regional issues/crises with potential impact on patient safety.
- Act as spokesperson and ambassador for the medicines / US both within and outside of GSK.
- Champion GSK's ethical and compliance standards such as ABAC.
Experience / Qualifications:
- Medical degree required with active medical license or equivalent
- Board Certification or equivalent in related oncology specialty is preferred
- Deep medical and scientific expertise to be viewed as credible by external experts and to provide sound medical judgement related to the therapeutic area
- Commercialization experience with solid knowledge of drug development, safety, regulatory/ market access and reimbursement requirements demonstrating deep understanding of the US market.
- Significant pharmaceutical and medical affairs experience
- Demonstrated effective communication, influence, leadership and talent development
- Demonstrated consistent strong performer and leader
- Proven ability to work in a matrix environment
- Strong organizational, planning, and business acumen skills
- Proven ability to interpret customer needs as well as negotiation and influence skills
- Flexibility and ability to adjust to changing timelines and priorities
- Ability to produce concise and simple summaries of concepts and solutions
- Ability to cope under pressure with sometimes conflicting priorities.
- Ability to prioritize business needs and flexibility to address them when business appropriate
- Ability to work with new technology and in the digital space
- Detailed working knowledge of GSK policies, Medical-specific policies, e.g. scientific engagement, preferred.
- Proven able to deliver effective and persuasive speeches and presentations on controversial or complex topics to top management and scientific audiences using original or innovative techniques or style.
- Adaptable to change - must clearly demonstrate ability to influence/lead directly to deliver results, proactively look for new opportunities and constantly anticipate the need for change.
- Continuous improvement - ability to drive a performance-based culture.
- Flexible thinking - ability to analyze external environment and translate to strategy and gain support of others to implement a vision. Must demonstrate good judgment.
- Customer driven - ability to understand patient needs and institutional concerns, integrate into strategies and build a team that is customer focused.
- Relationships building - ability to work effectively with others, delegate appropriately and foster a culture of collaboration.
- People development - ability to develop influencing/leadership skills in others, act as teacher, coach and mentor toward others.
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