Medical Director, Oncology Clinical Development, Belantamab Mafodotin

Site Name: UK - London - Brentford, UK - Hertfordshire - Stevenage
Posted Date: Jan 22 2020
Are you energized by the opportunity to apply your medical specialty expertise in a leading Immuno-Oncology research capacity currently in a pivitol trial ? If so, this Medical Director opportunity supporting a key asset could be an ideal opportunity to explore.

GSK has competitively advantaged assets in the immuno-oncology and epigenetic spaces. A further advantage is gained by an already established partnership with Merck to develop PD1 combinations (pembrolizumab is a market leading PD1 backbone), and our recent acquisition of Tesaro, thus adding their PARP Inhibitors and immuno-oncology therapies to our pipeline.

Oncology R&D at GSK is focused on building industry-leading portfolios in three cutting-edge areas of science:

  • Immuno-Oncology (IO): Invest to develop differentiated assets and combinations in increasingly crowded IO space.
  • Cancer Epigenetics: Take a more focused approach, pruning some existing assets while maintaining efforts in discovery and clinical development of most promising programs
  • Cell Therapy (CGT): Utilize competitive platform play based on patented technology.

Why you? The Medical Director is accountable for the clinical development of one the leading Oncology assets in Immuno-Oncology (IO): anti BCMA antibody drug conjugate (ADC), GSK2857916. The candidate will be responsible for leading clinical study team consisting of clinical scientists and other function representatives, strategizing development plan, executing clinical trial(s) in multiple myeloma and related diseases, and managing the development study resources and timeline. This role requires a cross-matrix leader to contribute to an integrated strategy across different indications for GSK'916, and to combination strategies with various internal and external assets.

We seek candidates with the following capabilities:
  • Vision and strategy: a passion to develop novel therapeutics for cancer patients. A deep understanding of adverse event management in areas of unmet clinical need and the ability to integrate this with the drug development activities required to advance compounds towards registration trials. Understanding of technical aspects relevant to drug development in the pharmaceutical industry including knowledge of GCP, regulatory processes (US and International) is highly desirable.
  • Leadership: Ability to implement the clinical vision and strategy. To lead a cross-functional team with integrity, flexibility and forthright communication. This requires exceptional interpersonal skills and the ability to meet project objectives by influencing and motivating key partners. Demonstrated alignment with and commitment to GSK Oncology vision and goals.
  • Judgment: evidence of good clinical and scientific judgment. Ability to interpret the significance of preclinical and clinical data, and to anticipate the information that will be needed to satisfy regulatory requirements for early and late phase oncology studies. Ability to progress project safely and efficiently. Know when to seek advice from colleagues and senior management.
  • Teamwork: to work as part of clinical development team, interact effectively across boundaries with other functions and disciplines using influencing, communication and relationship building skills. Able to secure, manage and maintain critical partnerships with key business partners.
  • Collaborate: to form collaborations with key external experts to take world class science and deliver meaningful benefits for patients.

Basic Qualifications:
  • Medical degree with sub-specialty in Oncology or Haematology
  • Strong pharmaceutical or relevant medical/clinical experience
  • Clinical and/or drug development experience with multiple myeloma is a plus
  • Good understanding of drug development
  • Relevant experience in early phase drug development and translational medicine is an advantage
  • Proven ability to strategize, prioritize, and manage multiple tasks simultaneously to ensure quality, timely, on-target and within budget execution
  • Managerial experience with demonstrated track record of successfully managing high-performance cross-functional matrix teams in a complex organization
  • Ability to embed medical functional skills and strategic thinking into team
  • Ability to discriminate between critical and non-critical activities and to follow established processes while identifying areas for process improvement
  • Attention to detail with excellent planning, time management and organizational skills
  • Excellent communication and presentation skills, high- level negotiation skills and the ability to resolve conflict in a constructive manner

Preferred Qualifications:
  • Haematologist

Why GSK?
Our values and expectations are at the heart of everything we do and form an important part of our culture.
These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Managing individual and team performance.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Implementing change initiatives and leading change.
  • Sustaining energy and well-being, building resilience in teams.
  • Continuously looking for opportunities to learn, build skills and share learning both internally and externally.
  • Developing people and building a talent pipeline.
  • Translating strategy into action - a compelling narrative, motivating others, setting objectives and delegation.
  • Building strong relationships and collaboration, managing trusted stakeholder relationships internally and externally.
  • Budgeting and forecasting, commercial and financial acumen.

As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able to succeed. We want all our colleagues to thrive at GSK bringing their unique experiences, ensuring they feel good and to keep growing their careers. As a candidate for a role, we want you to feel the same way.

We're open to all talent - whatever your gender, disability, marital status, religion or belief, age, race, sexual orientation, ethnic or national origin.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Please don't hesitate to contact us if you'd like to discuss any adjustments to our process which might help you demonstrate your strengths and capabilities. You can either call us on 0808 234 4391, or send an email

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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