Manager/Associate Director, Bioinformatics (Oncology)

    • Weston, MA

Site Name: USA - Massachusetts - Waltham
Posted Date: Jul 15 2020
Are you a highly experienced Bioinformatician with organizational, technological and scientific leadership in the application of state-of-the-art computation biology, committed to approaches in drug and biomarker development? Do you have a high level of integrity and desire to find new medicines that bring benefit to patients; a strong intellectual curiosity and desire to understand and solve problems? Does your background encompass broad expertise in Oncology and emerging enabling technologies? If so, the Advanced Analytics group of Experimental Medicine Unit (EMU) has an exciting opportunity as an Associate Director of Advanced Analytics and this could be an ideal for you to explore.

As an Associate Director of Advanced Analytics, you will have a willingness to work pro-actively in a fast-paced and dynamic matrixed work environment support the Niraparib program while evaluating patient stratification hypotheses and combination strategies. You will advance translational medicine efforts and lead a crucial component to the establishment of a high quality and collaborative expertise in data mining, data analysis, data visualization, computer programming, and computational biology applied across the GSK portfolio.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following :

  • Work with external resources to generate and analyze tumor genome/ transcriptome profiling data
  • Integrate with internal and external large scale non-clinical and clinical data sets to understand mechanism of compound response, to inform additional patient selection and enrichment marker development, additional indications, and rational combination strategies
  • Interact effectively with project teams across the portfolio
  • Develop and manage informatics platform to integrate external and internally acquired data in a format amenable to be used by scientists from research, EMU and medical development group across the portfolio in the organization.
  • Work with external resources to generate and analyze tumor genome

Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals:
  • PhD degree or equivalent Computational/Informatics experience/training with 7+ years of applied experience in Pharma/Biotech or academic setting. Minimum 1-2 years' experience in clinical research or clinical data management

Preferred Qualifications: If you have the following characteristics, it would be a plus:
  • Proficient in Python and R. Experience in oncology
  • Proven ability to influence across multi-disciplinary teams of internal colleagues and interact with external experts in academic institutions as well as CRO's
  • Experience in large scale, multi-dimensional genomic (including but not limited to NGS) and proteomic data analysis, integration and management.
  • Proficient in data visualization and communication with multi-disciplinary team
  • Ability to collaborate and apply leading algorithms from academic and industry
  • Creative and practical use of systems biology methods in gene/target discovery, interpretation of cellular processes, and biomarker discovery.

Why GSK?
Our values and expectationsare at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.


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