Investigator (In Vivo Pharmacology), Oncology

    • Waltham, MA

Site Name: USA - Massachusetts - Waltham
Posted Date: Jul 1 2020
Are you energized by the challenge of shaping and accelerating the scientific expertise of a biology program? If so, this Investigator opportunity could be an exciting opportunity to consider.

As an Investigator you will be responsible for providing advanced biology expertise to the selected biology group, and to develop and mentor a small group of biology professionals.

  • The Oncology Synthetic Lethality Research Unit has an opening for an In Vivo Pharmacologist at its Boston, MA site. The successful candidate will work together with a highly motivated team to discover and develop novel oncology drugs with a clear genetic relationship to cancer. The primary responsibility of this position will be to perform in vivo anti-tumor efficacy and PK/PD studies for to support multiple drug discovery programs. The candidate must be proficient in planning, executing and analyzing data from murine tumor model studies.

    Why you? Basic Qualifications:
    We are looking for professionals with these required skills to achieve our goals
    • PhD in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, or related life sciences field with strong scientific background in in vivo oncology or non-PhD with 10-15 years pharmaceutical experience
    • Demonstrated ability to design, conduct, and analyze data from in vivo pharmacology studies.
    • Strong organizational skills and the ability to manage multiple priorities in a matrix environment.

    Preferred Qualifications:
    If you have the following characteristics, it would be a plus:

    Scientific and Technical Competencies
    • Conducting in vivo studies to evaluate and establish efficacy, PK/PD relationship, combination strategy, biomarker identification and analysis
    • Perform ancillary in vitro and ex vivo assays to characterize effects of experimental medicines that may include Western blot, FACS other assays as needed
    • Quality documentation and Interpretation of experimental results
    • Presentation of results within a multidisciplinary team environment
    • Ensure appropriate use of animals in compliance with all regulatory requirements and internal standards

    Behavioral Competencies
    • Speaks, writes, and listens effectively in a variety of circumstances, sharing information and ideas with others.
    • All communication is delivered with clarity, impact & passion, and tailored to the audience.
    • Ensures that information is accurate & relevant by asking appropriate questions for clarification.
    • Maintains composure at all times when asking or answering questions
    • Listens to the views of others.
    Achieving Excellence
    • Enable & drive change
    • Creates a culture that values initiative & freedom of action & where a 'can do' attitude prevails.
    Drive for Results
    • Excellent record-keeping and organization skills
    • Applies rigorous judgment in assessing & prioritizing the science, projects & people.
    • Track record of taking intelligent risks, courage in personal decision making & willingness to be held accountable.

    Why GSK?

    Our values and expectationsare at the heart of everything we do and form an important part of our culture.
    These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

    • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
    • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
    • Continuously looking for opportunities to learn, build skills and share learning.
    • Sustaining energy and well-being.
    • Building strong relationships and collaboration, honest and open conversations.
    • Budgeting and cost-consciousness.

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