Biotransformation Mass Spectrometry Expert
- Stevenage, United Kingdom
Site Name: UK - Hertfordshire - Stevenage
Posted Date: May 14 2020
This is an exciting opportunity for a highly motivated biotransformation scientist, with extensive experience in metabolite identification using mass spectrometry, to join the Biotransformation Team based in Stevenage, UK.
The successful candidate will have a deep analytical background in high resolution mass spectrometry and metabolite identification with an established track record for designing, executing and interpreting bespoke biotransformation studies to aid medicinal chemistry design and key decisions impacting clinical development.You will be responsible for the delivery of critical in vitro and in vivo biotransformation data to influence and direct projects across the GSK portfolio.
- Provide mass spectrometry and metabolite identification expertise to the DMPK organisation
- Apply deep expertise to design and deliver metabolism studies in line with Discovery and Development DMPK key deliverables
- Understand, interpret, and communicate biotransformation data to Project Representatives and key stakeholders
- Be able to troubleshoot, problem solve and define best practice for biotransformation studies
- Drive innovation by investigating and implementing new analytical technologies and procedures
- Contribute to the scientific strategy to enhance the value of biotransformation science to support a diversified GSK portfolio
- Create internal and external networks to drive science within their discipline
- Author study reports
- Ensure data integrity and data accessibility through the GSK R&D data domains
- Ensure compliance with GSK Values and Policies
Closing Date for Applications: 30th May 2020
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
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- Proven ability of metabolite characterisation and quantification using high resolution mass spectrometry and state-of-the-art metabolite acquisition and processing software
- BSc or equivalent in Analytical Chemistry or Drug Metabolism and Pharmacokinetics
- Deep knowledge of biotransformations with proven experience applying this to drug discovery and development programs
- Good understanding of in vitro and in vivo approaches used to understand biotransformation issues
- Ability to work independently and problem solve with an extensive track record of generating high quality data and reports
- Excellent communication, interpersonal and team working skills
- MSc or PhD in relevant discipline
- Project or matrix leadership skills
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