Biotransformation Mass Spectrometry Expert

    • Stevenage, United Kingdom

Site Name: UK - Hertfordshire - Stevenage
Posted Date: May 14 2020
This is an exciting opportunity for a highly motivated biotransformation scientist, with extensive experience in metabolite identification using mass spectrometry, to join the Biotransformation Team based in Stevenage, UK.

The successful candidate will have a deep analytical background in high resolution mass spectrometry and metabolite identification with an established track record for designing, executing and interpreting bespoke biotransformation studies to aid medicinal chemistry design and key decisions impacting clinical development.You will be responsible for the delivery of critical in vitro and in vivo biotransformation data to influence and direct projects across the GSK portfolio.

Key Responsibilities:

  • Provide mass spectrometry and metabolite identification expertise to the DMPK organisation
  • Apply deep expertise to design and deliver metabolism studies in line with Discovery and Development DMPK key deliverables
  • Understand, interpret, and communicate biotransformation data to Project Representatives and key stakeholders
  • Be able to troubleshoot, problem solve and define best practice for biotransformation studies
  • Drive innovation by investigating and implementing new analytical technologies and procedures
  • Contribute to the scientific strategy to enhance the value of biotransformation science to support a diversified GSK portfolio
  • Create internal and external networks to drive science within their discipline
  • Author study reports
  • Ensure data integrity and data accessibility through the GSK R&D data domains
  • Ensure compliance with GSK Values and Policies

Closing Date for Applications: 30th May 2020

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.


Basic Qualifications:
  • Proven ability of metabolite characterisation and quantification using high resolution mass spectrometry and state-of-the-art metabolite acquisition and processing software
  • BSc or equivalent in Analytical Chemistry or Drug Metabolism and Pharmacokinetics
  • Deep knowledge of biotransformations with proven experience applying this to drug discovery and development programs
  • Good understanding of in vitro and in vivo approaches used to understand biotransformation issues
  • Ability to work independently and problem solve with an extensive track record of generating high quality data and reports
  • Excellent communication, interpersonal and team working skills

Additional Skills:
  • MSc or PhD in relevant discipline
  • Project or matrix leadership skills

As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able to succeed. We want all our colleagues to thrive at GSK bringing their unique experiences, ensuring they feel good and to keep growing their careers. As a candidate for a role, we want you to feel the same way.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class
(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Please don't hesitate to contact us if you'd like to discuss any adjustments to our process which might help you demonstrate your strengths and capabilities. You can either call us on 0808 234 4391, or send an email

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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