Vector Integration Analyst
Molecular biology skills including demonstrated experience of experimental design and processing of next generation sequencing (NGS) information and data analysis.
PhD or equivalent years of experience in Biological Sciences or computational biology.
GlaxoSmithKline (GSK) is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery for strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.
GSK's Advanced Therapy Delivery team is being expanded to support an increasing portfolio of cell and gene therapies. The team is responsible for delivering the Chemistry, Manufacturing and Controls (CMC) aspects of these therapies from early phase to market launch and the development of innovative technologies to enable step-change improvements to cell & gene therapy expertise and manufacture.
A highly motivated and independent individual is sought to work within this team. The successful candidate will be responsible for developing and performing analytical methods in order to:
- Sequence and map the location retroviral vectors in primary cells or cell lines tranduced with therapeutic vectors
- Develop novel approaches to understand and map retroviral integration sites
- Track cell populations, especially in the context of the hematopoietic system
The successful candidate is expected to have a strong background in molecular biology or computational biology including demonstrated experience in the design of experiments using NGS to study genomes as well as bioinformatic analysis of NGS data. Hands-on experience of NGS is essential, as is experience using linux systems. A strong interest in the manufacture of biopharmaceuticals and/or experience of working with integrating gene delivery vectors in a range of primary cells is also essential.
This position will report to the manager of Vector Integration and Genome Analysis, Cell and Gene Therapy platform and will be based at Stevenage in the UK.
During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process.
If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.
When applying for this role, please use the cover letter of the online application to describe how you meet the competencies required for this role as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
Thank you for your interest in this opportunity.
Closing date for applications: 19th September 2017
You may apply for this position online by selecting the Apply now button.
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