Senior Scientist /Associate Scientist

Basic qualifications:

Bachelor degree in Chemical Engineering, Biology, Chemistry, or other engineering or scientific field

Preferred qualifications:

1+ year(s) of direct GMP manufacturing experience or purification experience

  • Thorough knowledge of Good Manufacturing Practices (GMP) regulations
  • Thorough knowledge of routine laboratory/plant equipment and demonstrates high level of technical expertise with working familiarity with a number of methods, techniques, laboratory procedures and processes
  • Possess in-depth knowledge of how to analyze and interpret experimental/process data
  • Demonstrated ability to work as self-starter and handle multiple priorities in a dynamic cross-functional team based environment
  • Experience with GE platform of purification equipment and Unicorn software

Details:

Job Description:

The Associate Scientist leads the manufacture of clinical supply of investigational biopharmaceutical molecules. Specifically, hands-on cGMP mid to large scale purification of bulk drug substance for use in early phase clinical trials.

Key responsibilities include:

  • Performs hands-on processing of large scale purification steps under cGMP regulatory conditions. Processing steps include: Column packing, Chromatography, UltraFiltration/DiaFiltration, Depth Filtration, Bulk Drug Fill
  • Completes activities requiring independent thought that have the potential to comprise 50-100% of the employee's time depending on production campaigns
  • Leads or works on projects and assignments where independent action and a high degree of initiative and knowledge are required for execution or to provide recommendations
  • Supports the technology transfer process through active participation in ensuring that new processes fit and execute consistently
  • Manages daily activities within the area, including personnel efforts
  • Serves as floor lead during preparation and processing activities and potentially as area Supervisor, in the absence of the Supervisor
  • May be required to perform cleaning/sanitization of equipment and associated parts utilizing equipment washers, Clean-In-Place (CIP) systems as well as manual cleaning methods, on as-needed basis
  • May be required to prepares, assembles and sterilizes via autoclave of equipment and process components, on as-needed basis
  • May be required to prepare buffers, including weigh and dispense, formulation, and filtration activities, on as-needed basis

Specific Duties include:

  • Executes and overseas production of clinical supplies based on established scientific procedures and protocols and implements improvements with minimal supervision; interprets data and draws conclusions from the data
  • Anticipates/recognizes potential problems with equipment and/or supplies, and proactively seeks input from other Scientists to takes action to solve or prevent problems
  • Recognizes potential safety and compliance problems and takes action to rectify
  • Troubleshoots problems in the execution of processing activities; proactively assesses options and impact and takes action to rectify or communicate to appropriate decision makers
  • Authors Standard Operating Procedures (SOPs), Investigation reports, Safety Assessments, and various other protocols with minimal supervision
  • Reviews and approves executed load documentation (washer and autoclave), Buffer Forms, and/or Batch Records prior to submission to Quality Assurance (QA) to insure adherence to cGMPs and proper documentation practices

Contact information:

You may apply for this position online by selecting the Apply now button.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.


Meet Some of GlaxoSmithKline's Employees

Jasdeep

Procurement Associate

Jasdeep finds diverse suppliers to build GSK’s pipeline. He organizes joint ventures with companies and negotiates pricing rates and payments to build a seamless supply system for GSK’s materials and products.

Andrea

HR Associate, Future Leaders Program

Now in her second rotation of GSK’s Human Resources Future Leaders Programme, Andrea is shaping the future of talent management within Research and Development, from workforce assessments to strategy and operations.


Back to top