The current position is an opportunity for the appropriately qualified candidate to continue their professional development as a multidisciplinary medicinal and synthesis chemist in the setting of a drug discovery group.
This position is for a laboratory-based medicinal chemist in the Pattern Recognition Receptor DPU in the Immuno-Inflammation Therapy Area Unit.
This multidisciplinary role will work in partnership with high-throughput screening, biology, DMPK and medicinal chemistry teams to design, create and identify small molecule ligands for potential drug targets of interest to GSK.
This individual will plan and implement efficient synthetic routes to molecules of interest, scale up intermediates and/or candidates for advanced studies, and, when applicable, apply parallel synthesis, purification, and characterization techniques for lead validation and optimization (SAR generation).
Additional activities will include: setting priorities and coordinating work schedules with his/her supervisor in agreement with established priorities, developing new synthetic methods as needed, identifying and implementing innovative recent technologies, keeping a detailed laboratory notebook and cross-referenced data files and documenting the status of work through written and oral reports.
This individual will also develop an understanding of medicinal chemistry and relevant biochemical disciplines and establish and maintain a detailed knowledge of literature related to areas of research.
Excellent communication and presentation skills are essential.
The role requires a drive for continuous self-improvement and collaboration with other team members using a style that is positive and builds team members' confidence
• PhD degree in Organic Chemistry focused on natural product synthesis, bioorganic chemistry and/or synthetic methodology with 0 - 5 years industrial experience in medicinal chemistry.
Behaviors & competencies:
• Proactive, self-motivated, and organized
• High learning agility
• Experience developing other individuals (e.g. supervising a student)
• Expertise in synthetic organic chemistry typical of the PhD-level with demonstrated ability to creatively solve synthetic chemistry challenges; experience in applying emerging parallel synthesis, purification, and characterization techniques
• Candidates must be able to effectively work in a team environment and provide evidence to demonstrate how they work with chemistry team members.
• Demonstrated independence in decision making
• High level of scientific and personal credibility
• The candidate must have outstanding communication skills and be proficient in verbal and written English.
At GSK, our mission is to improve the quality of human life by enabling people to do more, feel better and live longer. Our three world-leading businesses research and deliver innovative medicines, vaccines and consumer healthcare products. We need a talented and motivated workforce to deliver against our strategy. To achieve this, we strive to attract the best people and to create an environment that empowers and inspires.
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