Manager, Cell and Gene Therapy (CGT) Research Projects US

Basic qualifications:

  • PhD (or equivalent) in molecular/cellular biology, virology, immunology, or a related discipline
  • Scientific: You will possess significant laboratory experience in cell and gene therapy research (>6yrs). Experience in one or more of the following disease areas: infectious diseases, renal disorders, liver disorders, metabolic disorders, neurosciences, immuno-oncology.
  • Good understanding and/or demonstrated experience with a wide range of state-of-the-art technologies used in cell and gene therapy, including gene delivery techniques (viral and non-viral), genome editing, or novel cell-based immunotherapies.

Preferred qualifications:

  • Project management: Evidence of driving program direction and delivery of significant packages of work to support the progress of novel therapeutics. Comfortable both leading and supporting project teams.
  • Teamwork: Demonstrated ability to interact effectively within a multi-disciplinary team and with other internal and external business partners using influencing, communication and relationship building skills. Demonstrated ability to multitask and react and adapt to changing priorities and business direction.
  • Communication: Attention to detail and good communication and documentation skills will be expected, as will be a flexible commitment to adding value within the role. Demonstrated ability to effectively communicate your work and data to various audiences in the form of presentations and written reports.
  • Problem Solving: Demonstrated ability to break down complex problems into achievable goals and provide effective solutions that meet the needs of our business partners.
  • Good understanding of the drug discovery and development process preferably in the area of cell and gene therapy.
  • Basic and proven understanding of intellectual property and data integrity to support asset progression through pre-clinical research/development.


The GSK Cell and Gene Therapy (CGT) Platform is an integrated discovery-development-supply unit within Pharma R&D which ensures that ground-breaking CGT medicines are seamlessly and expertly discovered and manufactured for clinical development and beyond. Our portfolio includes clinical stage assets in rare diseases and oncology, along with earlier stage programs in a variety of therapy areas.

Within the CGT Platform, the Cell & Gene Therapy Discovery Research (CGT-DR) team engages with all GSK therapy areas, to develop their pre-clinical portfolio from target through to clinical candidates. The group includes the Transgene Discovery, Transgene Delivery, Discovery Biology, Translational Research, and Research Projects lines. The focus for the Research Projects team is to provide the interface with GSK therapy areas, to brainstorm potential CGT approaches to therapy area targets, design projects, and to identify novel technologies in academia and from biotech companies that could enable or accelerate the discovery and development of future Cell and Gene Therapy medicines. Once projects are initiated, the Research Projects team often act as the CGT project co-lead with a therapy area co-lead to ensure project progression from target to clinical candidates.

We currently have an exciting position for a Manager in the CGT-Research Projects US group to support the developing portfolio of CGT projects within the oncology, infectious disease, renal and liver disease, and neuroscience therapy areas. The preferred candidate will work across multiple projects, primarily with a single therapy area focus, and will support all stages of project development from conception to execution. Review and due diligence of new external opportunities will also be part of this role.

You will have a strong desire to be involved in cell and gene therapy discovery projects and a willingness to engage with therapy areas to build programs, working as part of a multidisciplinary team. You will have a keen interest in cutting-edge CGT research and will be expected to maintain knowledge of current scientific literature relevant to the role. The ability to innovate and form productive interactions with scientists across GSK will be key skills for success in this role.

This US role will be based at the GSK Upper Providence or Upper Merion site in Pennsylvania, USA.

Closing date for Applications:

When applying, please use the "Cover Letter" in the on-line application to outline how you meet the requirements of the role. The information that you have provided in your cover letter and CV will be used to assess your application.

Thank you for your interest in this opportunity

Contact information:

You may apply for this position online by selecting the Apply now button.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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