Associate Scientist, BPT Lab
B.Sc., B.A. or equivalent degree in Biochemistry, Chemical Engineering, Chemistry or Biological Sciences is required.
>2 years industry experience required
Basic knowledge of biochemical purification techniques and of routine development laboratory procedures and/or plant equipment/operations is required.
Intermediate to advanced knowledge of protein purification, chromatography, scale down qualification, scale up, filtration and viral clearance.
Candidates with directly relevant employment, co-op or intern experience are preferred.
Familiarity with Akta Explorer/Pure and bioprocess skids is a big plus.
In addition, the successful candidate should possess:
A sound background in biochemistry, an enthusiastic attitude, the ability to plan, execute and analyze experiments; excellent verbal and written communication skills; and a desire to work in a team environment.
Job Description Summary-Job Category - Biopharmaceuticals: The field of research and development concerning biopharmaceuticals (medical drugs produced using biotechnology)
Job Family - Biological Sciences: Performs biological discovery and development research within a major or significant therapeutic area or a sub-speciality (e.g. biochemistry, cell biology, molecular biology).
Job Family Group - Science and Technology: Designs and executes studies to discover, understand, model, simulate, and create new drug molecules. Researches target identification, target validation, drug interactions with targets or receptors, and assay development. Maintains knowledge of competitive market conditions, patient requirements and technology advances.
The candidate will be involved in all aspects of purification process development for monoclonal antibodies (or other therapeutic proteins) including: initial process screening, optimization and characterization, viral clearance, validation, scale-up and tech transfer to clinical manufacturing and/or commercial manufacturing partners. Primary focus will be on purification unit operations such as column chromatography (affinity, ion exchange, HIC, etc.), filtration, ultrafiltration/diafiltration. Basic knowledge of GxP; basic knowledge of regulatory requirements of the pharmaceutical and/or biotechnology industry is beneficial.
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