Associate Scientist, Analytical Chemistry
Key responsibilities of the candidate include the following: 1) Support routine testing for development of game changer assets and provide HOS characterization for process development and comparability studies; 2) Develop methods for HOS characterization including aggregates and particles; 3) Perform forced degradation studies including protocol drafting, sample preparations, coordinate sample testing, perform assigned testing and aid in data analysis and interpretation.
A BS degree in protein biochemistry, biophysics, pharmaceutical sciences or related fields with 1-5 years of experience in biotech or pharmaceutical industry is required. Hands-on experience with various techniques for particle analysis and characterization including MFI, RMM and light obscuration. Good understanding of Biophysical technologies such as UV, fluorescence and/or light scattering. Knowledge of protein structure and degradation pathways. Sound understanding of the principle, instrumentation and data analysis/interpretation of biophysical technologies.
In-depth knowledge and experience in protein particle analysis and characterization using MFI, FlowCam, DLS, RMM and HIAC. Experience using Lumetics LINK software package. Sound understanding of structure analysis such as secondary and tertiary structure, protein folding-unfolding, using various spectroscopic and biophysical techniques including FTIR, CD, VCD, DSC, AUC, Fluorescence. Experience in characterization physical properties biopharmaceutical products. Experienced in analytical testing of Biopharmaceutical products using LC based methods.
At GSK, our mission is to improve the quality of human life by enabling people to do more, feel better and live longer. Our three world-leading businesses research and deliver innovative medicines, vaccines and consumer healthcare products. We need a talented and motivated workforce to deliver against our strategy. To achieve this, we strive to attract the best people and to create an environment that empowers and inspires.
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