Staff Scientist - McCune Lab

Requisition ID: 10350

Job Title: Staff Scientist - McCune Lab

Position Summary and Key Responsibilities:

The Staff Scientist is expected to function independently in developing and maintaining reliable research activities in the McCune pharmacokinetic research laboratory, which seeks to identify biomarkers for cancer prevention and treatment. The Staff Scientist is expected to work closely with the Principal Investigator (PI) and a team of Co-Investigator in several clinical subspecialties and research disciplines overcoming technical and organizational hurdles. The Staff Scientist will develop novel methods and use those methods to reliably quantitate drug and metabolite concentrations in biologic (mainly plasma) specimens. The Staff Scientist will work in a collaborative manner with clinical and laboratory staff to ensure efficient and proper sample collection from study participants. Data entry and basic data analysis are also required, as are providing basic support for preparation of grant proposals and manuscripts. The position will require extensive knowledge and experience in drug metabolism and pharmacokinetics, clinical chemistry/medical technology, and human subject research requirements. The tasks will require a high degree of skills in inter-personal communications, creativity in troubleshooting, and organizational ability.

Minimum Education and Skills Required for Consideration:

  • Bachelor's Degree in chemistry, biochemistry, pharmaceutical sciences, or medical technology.
  • Ph.D. Preferred
  • 5+ years relevant experience of relevant clinical and laboratory-based research experience.
  • Experience in liquid chromatography, mass spectrometry, and biosafety procedures;

Preferred Experience:

  • Developed novel methods to quantitate drug and metabolite concentrations in biological matrices, microsomal incubation, and pharmacokinetic analysis.
  • Basic knowledge of pharmacokinetics.
  • Familiarity with GLP and GCP requirements and experience in developing SOPs and quality control and assurance procedures.

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 4000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy. Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.


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