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City of Hope

Staff Scientist - Cell Signaling and Transcription Regulation in Development and Oncogenesis

3+ months agoDuarte, CA

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

A Staff Scientist position is available in a highly competitive research lab at City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers.

The successful applicant will join a highly competitive and productive research lab immediately to investigate molecular mechanisms underlying transcriptional control and cell signaling during cancer initiation and progression. The applicant will use "cutting-edge" and innovative genetically engineered mouse models and other advanced and unbiased biological approaches to uncover gene-expression and genomic and epigenetic alterations that regulate oncogenic transformation and related cellular events in tumorigenesis.

This Staff Scientist position is designed for very capable research professionals who have previous research experience, skills, and analytic ability to lead sophisticated research projects that are focused on the field of cancer biology and stem cell biology. The candidate should also have a proven track record of creativity and productivity, as well as previous experience in designing and performing daily experiments with GEM models. The candidate should be able to help the PI in drafting research proposals and manuscripts and evaluates research data and develops new experimental approaches. He/she should be able to work under stress in order to meet deadlines. He/she should also be able to assist the PI to train lab staff in specialized procedures, equipment and theoretical concepts behind unique tests. We provide a fruitful research and training environment and competitive salary and fringe benefit.

Basic education, experience and skills required for consideration:
  • Ph.D. or M.D/Ph.D. degree in Cancer Biology, Molecular Biology, Genetics, Biochemistry, Cell Biology, or a related field.
  • Previous experience with mouse models of human diseases, cancer biology, molecular biology, or genetics is highly desired.

Additional Information:
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability. #LI-MA


  • Posting Date: Dec 17, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

Job ID: CityOfHope-10011356
Employment Type: Other