Research Associate I

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

Requisition 13878

Research Associate I

Position Summary:

Our group in the Systems Biology Department in the Beckman Research Institute at the City of Hope is interested in comparative analyses of normal lymphocyte development and malignant transformation towards leukemia. We cover research areas with relevance to both Immunology and Hematology/Cancer Biology. We focus on signal transduction processes in normal and leukemic B cells as well as translational research directed towards childhood acute lymphoblastic leukemia (ALL). The successful candidate will assist laboratory research by providing technical assistance, preparing and arranging reagents, managing mouse colonies, ordering and inventory of stocks. More information:

Major responsibilities:

  • Assist in xenograft core management: Management of multiple stock colonies, coordination of material shipment with collaborators
  • Mouse handling includes husbandry, injections including drug-treatments, proficiency in collection of submandibular blood of mice
  • Bulk plasmid purification, PCR, gel electrophoresis, genotyping, Western blotting
  • Adherent and suspension cell culture maintenance general lab maintenance and ordering (i.e. restock lab reagents, maintain supplies stocks)
  • Test out new reagents/products for potential lab use
  • Additional consideration for applicants with previous clearance for animal irradiation and/or previous experience in flow cytometry for quantification of xenograft engraftment

Techniques may include, but are not limited to: basic molecular biology, biochemistry, aseptic techniques, immunofluorescence, immunohistochemistry, and microscopy. You will work under the direct supervision of a lab manager.

Under the direct supervision of the Principal Investigator, or designee, the Research Associate I performs a variety of routine and increasingly complex research experiments.

Essential Functions:
  • Utilizing laboratory equipment and established protocols, performs a variety of research experiments. Records and validates results for accuracy and completeness.
  • May modify protocols
  • Write standard operating procedures and reports.
  • Maintains records of work performed including results and methodology; utilizing records may calculate, graph and compile data.
  • Develops techniques and expertise in one or more areas relevant to laboratory research project.
  • Ensures that all laboratory activities are carried out in compliance with safety procedures and guidelines in handling, storage and disposal of materials.

Follows established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, includingadherence to theworkplaceCode of Conduct and Compliance Plan. Practices a high level of integrity and honesty in maintaining confidentiality.

Performs other related duties as assigned or requested.

The following shared, organization-wide competencies describe the desired behaviors that will facilitate success at City of Hope:
  • Communication - Expresses ideas clearly and constructively (written and spoken, upward and downward, one-on-one and with groups).
  • Customer Service - Seeks to understand customer needs and works to exceed customer expectations (internal and external).
  • Initiative - Looks for opportunities to improve performance; manages time, work, and relationships effectively and efficiently.
  • Professionalism - Treats others with respect; abides by the institutional values; displays a positive and cooperative attitude; adheres to the workplace Code of Conduct and compliance policies.
  • Stewardship - Identifies efficiencies to reduce redundancy and/or elimination of tasks resulting in savings of cost, resources, and or/time.
  • Teamwork - Works proactively and collaboratively with others to streamline work and achieve mutual goals.

  • Position Qualifications:

    Minimum Education
    • Bachelor’s degree in biological sciences

    Minimum Experience
    • 0-2 years of research/laboratory experience.
    • Bachelor's degree, Biological Sciences
    • Experience with genetic mouse models, cellular and molecular biology techniques
    • Meticulous record keeping, impeccable organization and proficiency with databases
    • Exceptional managerial and organizational skills
    • Excellent written and verbal communication
    • Strong work ethic, highly motivated, and work well independently and in a team.

    This is a full-time position with eligibility for paid leave and health benefits. Please reply with a cover letter and a CV.

    Skills: Other
    • Excellent computer skills

    Machines/Equip: Req./Pref.
    • Personal computer
    • Basic Laboratory equipment; such as
    • Centrifuge
    • Microscope

    Working / Environmental Conditions
    • Smoke free environment
    • May be exposed to toxic chemicals
    • Subject to regularly changing priorities or work assignments

    Protective Equip: May be Required
    • Must wear PPE as required

    • Excellent verbal and written communication skills
    • Excellent interpersonal skills.

    City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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