Research Associate I - Bioinformatics, Computational Biology - Wang Laboratory

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate,

patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
A Research Associate I position is available in the research lab of Leo D. Wang, M.D. Ph.D., at City of Hope. This position is focused on bioinformatics and computational biology of high-throughput / big data.

Our lab's research in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a secondary focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and use that knowledge to improve and devise new therapies for pediatric cancers and blood disorders.

To learn more about our research, visit: or

Key Responsibilities include:

  • Process and analyze high-throughput data from quantitative proteomic mass spectrometry. Primary use of Excel, R, Python as well as field-specific programs.
  • Adopt and adapt new programs from the field to incorporate into a processing workflow.
  • Communicate with experimentalists about results and biological importance.
  • Keep detailed and accurate logs of data and experiments from conception to analysis.
  • Help prepare presentations and written articles for publication.
  • Our team is collaborative, so all members assist in daily lab tasks and operations, including ordering, inventory, and other essential functions.
  • There may be some travel for inter-lab collaborations or trainings as well as funded conference opportunities.
  • The ability to do current research in proteomic bioinformatics and computational biology and implement new discoveries is critical for success in this position. There will be opportunities for research publications and presentations as well as collaborations with other research labs. Once established, there is potential to develop independent programs or projects.

Basic education, experience and skills required for consideration:
  • B.A./B.S. with background in computer science, statistics, and some biology.
  • Required knowledge of data structures and proficiency in a programming language for data science (R, Python).
  • Must be able to work meticulously, develop cohesive team relationships, communicate effectively in English, respond to and improve based on constructive feedback, and show dedication and commitment to our science.

Preferred education experience and skills:
  • Prior experience with big data or high-throughput data preferred.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national

origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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