Post-doctoral Fellow | Immuno-Oncology
About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nationâ€™s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.
Position Summary and Key Responsibilities:
The Postdoctoral Fellow position is available immediately in the Department of Immuno-Oncology at Beckman Research Institute in City of Hope Comprehensive Cancer Center, to explore mechanism of immune evasion in hematologic malignancies and to develop novel immunotherapeutic strategies. We seek applications from candidates with expertise in hematology and/or tumor immunology, with strong interests in translational research in animal models of human malignancies as well as in clinical studies. The environment of Beckman Research Institute is highly collaborative and these projects will involve multiple interactions with Hematologic Malignancies and Stem Cell Transplantation Institute at City of Hope and other research groups and core laboratories across our Institution.
The ideal candidate will be able to work independently on molecular and cellular mechanisms of immunosuppression in human and mouse models of myeloid- and B-cell malignancies utilizing the original oligonucleotide-based approaches for target validation. They can also participate in the ongoing clinical translation of first generation of immunogenic CpG-STAT3 inhibitors to B-cell lymphoma therapy. Skills in multicolor flow cytometry and/or computational biology (NGS data analysis) are an advantage. They will be responsible for drafting manuscripts, progress reports and presenting the results internally as well as extramurally when needed. Highly motivated individuals with strong communication skills and ability to work in high paced, multidisciplinary environment are invited to apply.
For more information about the laboratory and institution, please see our publications (e.g. Nature Med. 2018, Mol. Ther. 2018, Blood 2016; Clin. Cancer Res. 2015; Blood 2014; Nature Biotechnol. 2009) and the following links:
Minimum Education and Skills Required for Consideration:
â€ A Ph.D. degree in life or biomedical sciences, or a related discipline is required.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
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