Postdoctoral Fellow - Adipose Tissue Remodeling and Metabolic Disorders

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow in the laboratory of Dr. Qiong (Annabel) Wang, in the Department of Molecular and Cellular Endocrinology.

The Wang laboratory utilizes the cutting-edge tissue specific, inducible knockout and lineage tracing mouse models to study the region-specific remodeling of adipose tissue, both in physiological and pathological conditions, such as insulin resistance, obesity and cancer. Dr. Wang has previously generated the AdipoChaser mice model and tracked adipogenesis during adipose tissue development and remodeling (Wang QA, et al. Nature Medicine, 2013). Dr. Wang's another research revealed the surprising diversity of transcriptional signals required at different stages of adipogenesis in vivo (Wang QA, et al. Nature Cell Biology, 2015). The Wang lab is currently working on two projects: 1) Brown adipose tissue heterogeneity, and how this heterogeneity remodels the thermogenic capacity of brown adipocytes in health and disease. 2) White adipose tissue remodeling in the mammary gland during reproduction, and how this remodeling contributes to whole body metabolic disorders and breast cancer (Wang QA, et al. Cell Metabolism, 2018).

We are seeking a highly motivated postdoctoral fellow interested in studying the cellular and metabolic mechanisms leading to obesity, diabetes and cancer. The position requires extensive experience in molecular biology and rodent models.

Basic education, experience and skills required for consideration:

  • A Ph.D. degree in Molecular, Cellular, or Chemical Biology, or in life or biomedical sciences, or a related discipline is required.
  • Extensive experience with basic molecular biology skills.
  • Extensive experience in animal models.
  • Experience with immunofluorescence staining and flow cytometry.
  • Excellent written and verbal communication skills.
  • Good problem solving skills, ability to conduct independent research, ability to work effectively in a team.
Additional Information:
  • To apply, please include your CV and a list of three references.
  • For more information about Dr. Wang's research, please click here.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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