Cytogenetic Technologist I

    • Duarte, CA

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary:
Working as authorized by the Laboratory Director under Clinical Laboratory Improvement Amendments of 1988, CFR Section 493.1445(a). Uses established cytogenetic/molecular genetic methodology to perform and interpret a variety of standardized clinical laboratory tests for the purpose of postnatal diagnosis of chromosomal aberrations, molecular genetic disorders and diagnosis/prognosis of cancer and preneoplastic syndromes.

Key Responsibilities include:

  • Selects suitable cells for analysis and performs accurate counts and analysis of banded chromosomes at the microscope.
  • Selects suitable cells for analysis and performs analysis of fluorescent patterns at the microscope and on the FISH equipment.
  • Prepares and processes biological specimens for molecular and genetic analysis using established molecular techniques and biohazard, aseptic and culturing procedures. Determines optimum time sequence for harvesting procedures; assesses chromosome quality.
  • Performs and selects appropriate tissue culture and harvesting techniques for a variety of cells and tissue types.
  • Performs and selects chromosome banding methods to provide differentiation of chromosome pairs. Selects additional staining methods as requested.
  • Operates and maintains conventional and inverted microscopes as well as photomicrograph, ASI equipment; BioView equipment and AI equipment.
  • Prepares karyotypes, recognizes abnormalities of chromosome number and structure, and is able to differentiate chromosomal abnormalities from normal chromosomal variants. Uses ISCN cytogenetic nomenclature in preparing report of results.
  • Determines the need for further studies to complete a diagnosis, with the appropriate authority.
  • Accessions cases utilizing a computerized data base
  • Prepares culture media, reagents and stains as necessary. Prepares laboratory reagents to proper concentration and pH as assigned.
  • Performs cryopreservation of cells when necessary.
  • Performs or participates in quality control, quality assurance, or quality improvement procedures.
  • Maintains professional growth and development through seminars, workshops, and professional affiliations to maintain certification/licensure, and/or keep abreast of latest trends in field of expertise.
  • Attends departmental meetings as required and participates in the department continuing education program.
  • Follows established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, including adherence to the workplace Code of Conduct and Compliance Plan. Practices a high level of integrity and honesty in maintaining confidentiality.

Basic education, experience and skills required for consideration:
  • Bachelor’s degree in a Chemical, Physical, Biological, Clinical Laboratory Science or Medical Technology
  • Clinical cytogenetic technical experience (minimum of 1 year experience of chromosome analysis) under a qualified director
  • Thorough understanding of procedures to perform/prepare biological specimens for genetic analyses
Required Certification/Licensure:
  • CG(ASCP)CM Certification
  • Clinical Cytogenetics Scientist License (California State License)

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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